Non-A, non-B hepatitis markers in the east of Scotland.
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Biomedical subjects
Publications and source records attributed to R Hopkins.
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Commercial 125I anti-HBs was processed to yield a sixfold improvement in economy without significant loss of sensitivity or specificity. Additional polystyrene beads were coupled with commercially supplied anti-HBs. The modified assay (Mod-RIA) was compared with commercial RIA, EIA, and RPHA using established HBsAg panels. Mod-RIA was also compared with HEPATEST (RPHA) for screening 71 200 fresh blood donations during an 11.5-month period.
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The opinions of 600 randomly selected doctors on what should be taught to undergraduates in clinical years were analysed. The respondents gave a high priority to general medicine, paediatrics, general surgery, casualty, and gynaecology, but a low priority to forensic medicine, plastic surgery, radiotherapy, anaesthetics, radiology, and rehabilitation medicine. Doctors thought that these should be taught to postgraduates. The two major groupings of doctors--general practitioners and consultants--gave essentially the same priorities. Undergraduate curricula cannot include all major specialities, so the results of this analysis may provide a useful basis for selecting the most suitable subjects. Criteria for including other specialties might be the ability and enthusiasm of the teachers and well-thought-out and academically sound teaching programmes.
The effect of indomethacin suppositories was observed in 102 patients. Some patients had rectal irritation (9%), and a few had difficulty in inserting the suppository. Most patients tolerated the medication well with relief of joint symptoms (the major reason for prescription) and usually with alleviation of dyspepsia (the second commonest reason for giving the drug in this way).
Human group O rhesus negative erythrocytes were spherocyted and fixed in glutaraldehyde, then coated initially with HBsAg and subsequently with anti-HBs. The resulting reagent was found to agglutinate in the presence of HBsAg positive serum, but not in HBsAg negative serum. The assay was evaluated for blood donor screening (39,962 donations) over a 6-month period, and was compared with Hepatest (RPHA) and AUSRIA-2 (RIA) for the study of two established HBsAg panels.
Seven different types of lecturing technique were assessed in 14 groups of nurses at 2 hospitals. Two lectures in rheumatology were given to each group and a multiple choice questionnaire answered by the nurses immediately after the lecture and 3 months later. A significant amount of knowledge was imparted by the lecturer. About a third of the knowledge, however, was lost within a minute of the end of the lecture, and a half to two-thirds within 3 months. There was no correlation between scores and the row on which the students sat. There was no significant difference between the scores of overseas students and those of British nurses. At immediate recall the techniques differed little. The techniques which scored best were giving the questionnaire before the lectures, giving handouts and using the blackboard. At delayed recall 100% differences in marks were seen between the worst and best techniques in the second lecture. The same techniques which scored best at immediate recall did so on delayed recall. The lowest score occurred where note taking was forbidden. Some questions scored significantly better with note taking. When note taking was forbidden, it made no difference if the student was an habitual notetaker or not. Nor did it make any difference if she was frustrated by the ban. There was no correlation between entry qualifications and the scores obtained. Nurses at a non-teaching hospital did just as well as those at a teaching hospital. It should be emphasised that teaching endeavours to influence 3 aspects-knowledge, skills and attitudes. This series of experiments largely tests the first, but does suggest that a technique which scores highly on information recall may be less helpful in forming constructive attitudes to the patient.
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