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Biomedical subjects

R Hoff

Publications and source records attributed to R Hoff.

63 records · Page 4Linked to original sources
PubMed1978

Trypanosoma cruzi infection in dogs and cats and household seroreactivity to T. cruzi in a rural community in northeast Brazil.

The prevalence of Trypanosoma cruzi parasitemia as determined by xenodiagnosis on domestic dogs and cats was correlated with household rates of seroreactivity to T. cruzi and household Panstrongylus megistus infestation in a rural area in northeast Brazil where P. megistus was the only domiciliary triatomine vector. T. cruzi infection was present in about 18% of domestic dogs and cats. Two-thirds of seroreactive children below age 10 resided in houses with T. cruzi-infected animals. In houses with a T. cruzi-infected dog or cat, as well as at least one infected P. megistus, the household rate of seroreactivity to T. cruzi was five times greater than in houses with non-infected domestic animals and no infected triatomine vectors. Domestic dogs and cats are important reservoirs of T. cruzi in an endemic area where P. megistus is the only domiciliary triatomine vector.

Adult↗
PubMed1976

Teaching sex education and counseling for the primary physician.

Today's family physicians are being confronted by increasing numbers of patients who desire and need sex education and counseling. It is suggested that the family and primary physician can approach the multiple sex-related needs of the family by understanding the family life cycle and by using permission-giving, limited information, and specific suggestions with patients as needed and as appropriate. The experience of the University of Miami's Department of Family Medicine in teaching human sexuality to medical students, residents, and faculty of the medical center is cited to help other residency programs include sex counseling and sex education in the armamentarium of residents.

Adolescent↗
PubMed1975

Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo.

Peritoneal macrophages from T. cruzi-immune mice were resistant to infection in vitro with culture forms of the parasite. Macrophage resistance appeared in infected mice about 21 days postinfection when parasitemia was still rising. Resistance in vitro was nonspecific since macrophages from BCG-immune mice were resistant to T. cruzi, and since macrophages from T. cruzi-immune mice were resistant to infection in vitro with Listeria were not resistant to challenge with T. cruzi even when the parasites were opsonized.

Animals↗
PubMed1975

Role of complement components in the susceptibility to Plasmodium berghei infection among inbred strains of mice.

Inbred strains of mice, sensitive and resistant to Plasmodium berghei infections, including a complement deficient strain were infected with P. berghei. Daily levels of parasitaemia were determined and serum levels of complement components (C3 and C5) measured by standard haemolytic assay. Serum levels of C3 and C5 were depressed in all strains of mice infected with P. berghei. There was no difference in the infectivity and course of P. berghei infection in the co-isogenic C5 deficient and non-deficient strains. The significance of these observations is discussed.

Agglutination Tests↗
PubMedDate not supplied

Frozen maternal platelets for neonatal thrombocytopenia.

A case is reported of an alloimmunized, neonatal, thrombocytopenic patient who was successfully transfused with maternal platelets collected by cytapheresis and cryopreserved 3 months before delivery. Phlebotomy or cytapheresis of the mother immediately before delivery was avoided. Transfusion of maternal platelets over a 7-day period with aliquots containing an average of 7.1 X 10(10) platelets in 50 ml of plasma was possible. Satisfactory increases in platelet counts were sustained after transfusion.

Adult↗
PubMedDate not supplied

HIV seroprevalence surveys of childbearing women--objectives, methods, and uses of the data.

A seroprevalence survey of human immunodeficiency virus (HIV) among childbearing women is being conducted in 43 States and Territories as one of the family of HIV seroprevalence surveys. This blinded survey, in which serologic test results are not linked to identifiable persons, uses neonatal dried blood specimens on filter paper to test for maternal antibodies to HIV. This survey provides relatively unbiased estimates of prevalence of HIV infection in the population of women delivering live children during given survey periods, by month or quarter of delivery, geographic area, and demographic subgroup. This objective will be met while protecting the integrity and efficient conduct of neonatal screening programs and ensuring patient anonymity. Information from this survey will be used to (a) assess the levels and trends of HIV infection in women and infants, (b) help develop and evaluate prevention programs, and (c) project the number of women and children who will develop HIV infection and the acquired immunodeficiency syndrome (AIDS) and will require health care and social services in the future.

Acquired Immunodeficiency Syndrome↗