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Biomedical subjects

R Haye

Publications and source records attributed to R Haye.

34 records · Page 2Linked to original sources
PubMed1977

Vascular reactions to horseradish peroxidase in the guinea pig.

Albino guinea pigs were given intradermal injections of the protein tracer horseradish peroxidase. In a 0.1 mM concentration the tracer did not increase vascular permeability to Evans blue-labelled plasma proteins. In a 1 mM concentration, however, the peroxidase induced a local vascular leakage. This leakage was almost totally inhibited by pretreating the animals with acetylsalicylic acid, while antihistamine had only a weak inhibitory effect. We therefore believe that prostaglandins are important mediators in this HRP-induced vascular reaction.

Animals↗
PubMedDate not supplied

The natural course of Meniere's disease.

The case history and disability of 111 patients suffering from Meniere's disease are reported. Observed for more than 5 years, the patients have had no, or only medical treatment, in most cases of short duration. The number of patients disabled and their degree of disability seems to justifiy surgical treatment in patients with frequent and incapacitating attacks of vertigo.

Adult↗
PubMedDate not supplied

Experimental nasal septoplasty; influence on nasomaxillary development. A roentgen cephalometric study in growing domestic cats.

The fear of destroying an anticipated growth centre has, with time, induced the postponement of nasal septal operations until adult age. Underdevelopment of the nose and middle face is otherwise believed to be the long-term result. In order to test this hypothesis, subepichondrial surgery was performed in growing domestic cats. The technique resembled modern corrective interventions for septum deviations in humans. Based on cephalometry, i.e. measurements on lateral skull radiograms, no significant influence could be found regarding ultimate nasal or mid-facial dimensions. The findings tentatively intimate that septal surgery might be carried out at a much earlier age than hitherto assumed.

Age Factors↗
PubMedDate not supplied

Experimental septoplasty in the growing cat. A histological study.

Surgery on the nasal septum of a child is still a controversial issue, due to the fear of nasal growth inhibition. To elucidate the role that the Cottle premaxilla approach septoplasty play in the long term result, an operation using this technique was done in the growing cat, but no nasal packing nor stenting was applied. In several cases postoperative sequelae occurred, such as septal perforations, synnechia and thickening of the septum, due to dislodged cartilages. The complications were judged to be minor relative to the overall results. They have, however, to be carefully considered and weighed against the benefit of the operation.

Animals↗