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Biomedical subjects

R Harrison

Publications and source records attributed to R Harrison.

295 records · Page 17Linked to original sources

Relevance of pharmacokinetics to prescribing in psychiatry.

Pharmacokinetic characteristics of psychotropic drugs, including their absorption, distribution, metabolism and elimination, vary greatly between drugs and between individual patients. Consideration of these factors is necessary for the rational prescribing of drugs in psychiatry and can prevent potentially dangerous drug interactions.

Drug Interactions↗

Anterior dental crossbite: relationship between incisor crown length and incisor irregularity before and after orthodontic treatment.

The purpose of this study involving a sample of children with single central incisor crossbite was to determine the relationship between clinical crown lengths of the crossbite and noncrossbite mandibular incisors, incisor irregularity, and orthodontic correction of the crossbite. In addition, for comparison, the normal maturational change in position of the labial gingival margin of mandibular incisors not undergoing orthodontic correction was examined. Twenty-one children treated for single central incisor crossbite were matched individually by gender and age to a comparison group. Pre- and post-treatment mandibular central incisor crown lengths and incisor irregularity were measured. In 10 of the 21 anterior crossbite cases, the crown length of the crossbite incisor was more than 1.5 mm greater than that of the noncrossbite incisor. This difference improved with orthodontic treatment by a combination of apical movement of the gingival margin of the noncrossbite incisor (0.9 +/- 0.8 mm) and coronal movement (0.2 +/- 0.6 mm) of the gingival margin of the crossbite incisor. In contrast, for the remaining 11 anterior crossbites without such a crown length difference, and for the comparison cases, the gingival margins of both mandibular central incisors moved equally from pre- to post-treatment by 0.5 +/- 0.5 mm in an apical direction. Pretreatment crown length difference between crossbite and noncrossbite incisor was associated strongly to incisor irregularity (P < or = 0.005, r = 0.65). Orthodontic correction of the crossbite produced an improvement in irregularity index (IR) that was greatest in those anterior crossbite cases with a pretreatment crown length difference.(ABSTRACT TRUNCATED AT 250 WORDS)

Child↗

Respiratory health hazards and lung function in wildland firefighters.

The authors discuss the multitude of contaminants to which wildland firefighters are exposed, including carbon monoxide, sulfur dioxide, particulate and silica, polyaromatic hydrocarbons, aldehydes, and benzene. They examine the respiratory effects of these contaminants and then present their recommendations for an occupational health program for wildland firefighters.

Environmental Monitoring↗

Feeding practices and dental caries in an urban Canadian population of Vietnamese preschool children.

The aim of this project was to determine the severity of nursing caries, and to examine contributing behavioral factors, in a group of Vietnamese families in British Columbia, Canada. The data collected became the basis for a community-based oral health promotion program. Information on feeding, dental health practices, and dental caries were collected for 60 mother/child pairs. For children > or = 18 mos, prevalence of nursing caries was 64 percent. Sixty-five percent of all children had a naptime bottle, and 85 percent > or = 18 mos had a "comfort" bottle that was carried around, and drunk from during the day. Milk was the most common beverage. A "comfort" bottle was significantly related to the presence of nursing caries, P = 0.02; a naptime bottle had a less significant association, P = 0.07. Dental knowledge questions revealed that all mothers knew that a child who had a "comfort" bottle could get tooth decay, but 63 percent thought that cavities were not a problem in baby teeth.

Animals↗