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Biomedical subjects

R Hardern

Publications and source records attributed to R Hardern.

8 recordsLinked to original sources
PubMed1996

Oxygen saturation in adults with acute asthma.

Avoidable deaths from asthma continue. Some of these result from the difficulty in determining the severity of an acute asthma attack at the initial assessment. This study evaluated the relation of pulse oximetry with other markers of severity in 46 patients attending an accident and emergency (A&E) department with acute asthma. Neither oxygen saturation nor peak flow correlated with length of admission or with other "retrospective" markers of severity. Attempts to collect follow up data (for example, peak flow charts) from patients discharged from the A&E department failed. It proved impossible to determine whether pulse oximetry predicts which adults can be discharged.

Adult↗
PubMed1995

Ecstasy toxicity.

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3,4-Methylenedioxyamphetamine↗
PubMed1993

Hyperthermia associated with 3,4-methylenedioxyethamphetamine ('Eve').

A patient was admitted with hyperthermia, muscle rigidity, rhabdomyolysis and disseminated intravascular coagulation. He was initially thought to have taken 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), but subsequent toxicology revealed the presence of 3,4-methylenedioxyethamphetamine (MDEA, 'Eve'), its sister drug, in his blood. Subsequent in vitro testing for malignant hyperthermia proved to be negative.

3,4-Methylenedioxyamphetamine↗
PubMedDate not supplied

Thrombolysis nurse.

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Emergency Service, Hospital↗
PubMedDate not supplied

Doctors, nurses, and training in the administration of intravenous drugs.

To assess the knowledge of staff and the effect of formal training on house officers we conducted telephone questionnaires of 40 house officers and 18 nurses. The following points were assessed: knowledge of dilution of drugs; knowledge of the rate at which drugs should be given; and the rate at which drugs were given. Appropriately trained nurses had greater knowledge than 'untrained' house officers. In all, 17/18 (94%) nurses compared with 9/18 (50%) house officers knew the correct rate at which to give ampicillin (P = 0.0036, Fisher's exact test); 14/18 (78%) nurses and 1/18 (6%) house officers said they gave ampicillin at the correct rate (P < 0.001); 13/18 (72%) nurses and 7/18 (39%) house officers said they gave ranitidine at the correct rate (P = 0.037). Only 1 of the 10 house officers who knew how rapidly to administer ampicillin said they took the correct length of time; 6 of the 10 who knew how rapidly to give ranitidine said they gave it at the correct rate. Training improves the knowledge of house officers, but other factors besides lack of knowledge (possibly lack of time) adversely affect delivery of intravenous drugs.

Education, Nursing↗