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Biomedical subjects

R Haley

Publications and source records attributed to R Haley.

10 recordsLinked to original sources

Perceptions of influenza and influenza vaccination in patients attending hospital outpatient clinics.

Influenza remains a major cause of morbidity and disruption to health services during winter. Annual vaccination of risk groups is the mainstay of influenza management policy. Despite much national publicity, vaccine uptake remains below desired levels. We investigated the perceptions of influenzal illness and opinions on vaccination in hospital outpatients attending clinics associated with risk and non-risk (i.e. control) morbidities. There were 270 recruited patients in risk groups: 90 each from diabetic, respiratory and cardiac clinics and equal numbers in three age groups (40-49, 50-59, 60-69 years). Equal numbers of controls were recruited from colorectal, fracture and dermatology clinics. The perceptions of influenza and knowledge of the preventive value of vaccination were fairly accurate in both groups. Fewer people in both groups had been vaccinated than had been specifically advised to be vaccinated. Advice for vaccination had been received by fewer people attending the cardiac clinic than the other two risk associated clinics. More use could be made of the health education opportunity afforded by attendance at hospital outpatient clinics.

Adult↗

Evaluation of the gemini infusion pump for the safe delivery of peripheral blood progenitor cells (stem cells).

The purpose of this in vitro study was to determine whether the Gemini PC-2TX infusion pump could safely deliver peripheral stem cells (PSC) for an autologous PSC transplant. For purposes of hypothesis testing, it was assumed that there would be no significant difference in CD34+ cell counts and colony-forming units-granulocyte, macrophage (CFU-GM) when the PSCs were administered by an IMED PC-2TX infusion pump as opposed to an intravenous push method. The American Red Cross collected 50-ml samples of PSCs from four donors by apheresis. These cells were tested for CD34+ using flow cytometry and for functional progenitor cells using a CFU-GM assay. The cells were cryopreserved after testing. For our study, samples were tested simultaneously at a single facility. Each sample was individually thawed and a baseline thaw sample collected; 10 ml of the donor specimen was pushed through a syringe into a specimen container (intravenous push sample). The remainder of the specimen was infused through the IMED Gemini PC-2TX pump into a specimen container (intravenous pump sample). All samples were assayed for CD34+ cell counts and CFU-GM. Data analyses were conducted using the t-test for paired samples, with values of P < 0.05 considered significant. Results failed to demonstrate a statistically significant difference between the CD34+ or CFU-GM results of the intravenous push and intravenous pump specimens. Additionally, we failed to find a statistically significant difference when we compared the intravenous push and the intravenous pump specimens with the baseline thaw sample. The results of this study support the hypothesis that the Gemini PC-2TX infusion pump can safely deliver PSCs for the purposes of stem cell transplantation.

Antigens, CD34↗

DSM-III disorders in a large sample of psychiatric patients: frequency and specificity of diagnoses.

This study examined certain nosological features of DSM-III axis I diagnostic categories and subcategories as applied to 11,292 general psychiatric patients presenting for care, using a semistructured assessment procedure. The most frequently used major categories were affective, substance use, childhood-onset, and adjustment disorders. Secondary diagnoses were given to 26% of the patients. Male patients predominated in the categories of impulse-control, psychosexual, and substance use disorders, and female patients predominated in the categories of anxiety, affective, and somatoform disorders. Of the 329 five-digit subcategories available in DSM-III, 296 (90%) were actually used. Sixteen percent of the patients were given unspecific primary diagnoses.

Adolescent↗

Correspondence between parents' reports on the Behavior Problem Checklist.

Interparent agreement on the Behavior Problem Checklist (BPC) was assessed in relation to several potentially influential variables. Major findings indicated parent agreement to be of a moderate level, generally higher in nondistressed than distressed samples, lower on Personality Problem items than Conduct Problem items, very low regarding presence of specific behaviors, and importantly related to type of reliability index employed. Issues deserving additional research effort are discussed.

Adolescent↗

Mid-life women doctoral students rediscover "voice" in a community of scholarly caring.

Recent research indicates that doctoral study is for many "an excessively painful rite of passage" for which an "indefensible human price is exacted." For mid-life women doctoral students in nursing and education doctoral programs, this human price is sometimes paid in the currency of loss of personal voice. Because they often assume leadership positions after graduation, it is a significant loss to the professions when these women's mature voices are lost or even temporarily silenced. This article describes the design, findings, evaluation, and implications of an emancipatory inquiry entitled "Gifted Women: Doctoral Study As Heroic Journey." Simultaneously a participatory research project and curricular innovation, this unique 18-month project joined facilitators and participants as coresearchers in a workshop and four reunions that integrated feminist process with expressive, esthetic approaches. The results of this emancipatory inquiry showed that viewing doctoral study as a heroic journey enlightened these mid-life women participants to reclaim their personal voices, empowered them with the support of a community of scholarly caring, and emancipated them to undertake personally meaningful and scholarly dissertation research.

Adult↗