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Biomedical subjects

R H Sutton

Publications and source records attributed to R H Sutton.

At least 55 records · Page 3Linked to original sources

Cryptococcosis in dogs: a report on 6 cases.

The main features of Cryptococcus neoformans infection in 6 dogs, all of which were of large breed, were central nervous system involvement in all cases and diversity of the initial presenting signs. The respiratory tract was affected in one case, but the bronchopneumonia did not appear to be of cryptococcal origin. Immunosuppressive factors and other diseases which are believed to increase the susceptibility of man and animals to cryptococcal infection did not appear to be of importance in these cases.

Animals↗

A protracted case of cryptococcal nasal granuloma in a stallion.

A 13-year-old Standardbred stallion presented with a unilateral mucopurulent nasal discharge and airway obstruction was found to have an extensive cryptococcal nasal granuloma. Treatment was not attempted. The stallion was destroyed 26 months later having completed 2 successful breeding seasons. The granuloma had gradually increased in size and almost completely occupied the left nasal cavity and paranasal sinuses. It was characterised histologically by fibrous and myxomatous tissue and masses of yeasts. A cryptococcal granuloma found within the wall of the jejunum could represent evidence of dissemination, and organisms were seen within alveoli, bronchioles and the intestinal lumen.

Animals↗

The effect of Eperythrozoon ovis infection on the glucose level and some acid-base factors in the venous blood of sheep.

Eperythrozoon ovis infected sheep have low venous blood glucose levels and correspondingly increased blood lactic acid levels as compared with control sheep. Acid-base studies showed that these changes were accompanied by significant falls in venous pH, and standard bicarbonate as well as a negative base excess. All these changes were considered to result from the increased alvcolytic activity of infected erythrocytes. The acidosis and hypoglycaemia associated with E. ovis infection, while not having any apparent effect on young, well-fed sheep, could be potentially serious in pregnant ewes and in sheep on a low plane of nutrition.

Acid-Base Equilibrium↗

The estimation of fibrinogen levels in animal plasmas by a simple refractometric method. A comparison with a biuret method.

A comparison was made between a biuret (reference) method and a simple refractometric (test) method for measuring fibrinogen levels in 84 animal plasmas. Although the correlation between the two methods was high (4=0.90 P less than 0-001) there was considerable random variation in the refractometric results in relation to the biuret results. This was thought to be due in part to the fact that refractometric results could only be expressed in multiples of 2.4 g/litre. In spite of this limitation, the refractometric method, on the grounds of speen and simplicity, is considered to have worthwhile application for fibrinogen determinations in practice laboratory.

Animals↗

Eperythrozoon ovis: the difference in carbohydrate metabolism between infected and uninfected sheep erythrocytes.

The glucose utilization lactic and pyruvic acid production and oxygen uptake of normal and Eperythrozoon ovis infected sheep erythrocytes were measured under aerobic conditions. Infected cells showed marded increases in both glucose utilization and acid production as compared with controls. Uninfected erythocyte samples which included a percentage of reticulocytes comparable to that found in E. ovis infection showed no apparent difference in glucose utilization and lactic acid production form the normal control erythrocytes, although considerable increases in the oxygen uptake were recorded.

Anaplasmataceae Infections↗