Biomedical subjects
R H Seville
Publications and source records attributed to R H Seville.
Treatment of erythrasma with miconazole.
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Topical glucocorticosteroids for psoriasis.
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Psoriasis and stress. II.
A retrospective assessment of insight was undertaken in 61 patients whose psoriasis was considered to have been precipitated by stress. A significantly better prognosis was observed in those patients assessed as having had insight.
Psoriasis and stress.
132 psoriasis patients who had been completely cleared with dithranol were assessed and then followed up over a 3-year period. The incubation time from specific incidents of stress to the development of psoriasis was between 2 days and 1 month. Specific stress within a month before the first attack was recalled by 51 patients (39%); chance association was excluded by studying a control group where there was significantly less specific stress. The prognosis for the psoriasis patients who recollected specific stress a month prior to the onset was significantly better than for the rest of the patients where none had been recalled.
Relapse rate of psoriasis worsened by adding steroids to a dithranol regime.
The rate of relapse after dithranol therapy is significantly less that when betamethasone valerate under occlusion is combined with ditrhanol in the treatment of psoriasis. It is also argued that local steroids are inferior to deithranol in the management of psoriasis.
Simplified dithranol treatment for psoriasis.
Progressive simplification of dithranol therapy has made treatment at home more acceptable. This has included ommitting ultra-violet light, talc and dressings, and substituting an ordinary bath instead of one containing tar. A stiffened dithranol 0.5% ointment was found to be slightly more effective than the best paste hitherto employed. It was also very much easier to use.