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Biomedical subjects

R H James

Publications and source records attributed to R H James.

At least 37 records · Page 2Linked to original sources
PubMed1989

Apnoea after retrobulbar block.

Two cases of apnoea after retrobulbar block for cataract surgery are described. The possible causes and mechanisms of this complication, its detection and management are discussed.

Aged↗
PubMed1988

Variables associated with ultraviolet transmittance measurements of intraocular lenses.

We measured the spectral transmittance of 12 intraocular lenses with a spectroradiometer system that uses an integrating sphere input. We evaluated both low- and high-power lenses and varied the input aperture size between 1, 3, and 5 mm. These variations caused a significant difference in the transmittance characteristics of the intraocular lenses. Most significantly, the transmittance of the low-power model was two to six times greater than that of the high-power model in the cutoff region. The larger aperture resulted in, at most, a factor of two difference in transmittance. This effect was observed in intraocular lenses labeled both ultraviolet-absorbing and nonultraviolet-absorbing.

Absorption↗
PubMed1988

The lower oesophageal sphincter in the first trimester of pregnancy: comparison of supine with lithotomy positions.

Measurement were made of gastric pressure (GP), lower oesophageal sphincter pressure (LOSP) and barrier pressure (BrP) in the supine and lithotomy positions in 17 healthy women undergoing termination of pregnancy in the first trimester. Values in the supine position were similar to those seen in non-pregnant subjects, but there was a significant reduction in LOSP and BrP in the lithotomy position unrelated to any change in intragastric pressure. It is concluded that the lithotomy position is associated with increased risk of regurgitation in early pregnancy.

Adolescent↗
PubMed1987

Single oral dose pharmacokinetics of tiapride in patients with Huntington's disease.

The pharmacokinetic properties of a single oral dose of 100 mg of tiapride were studied in six patients with Huntington's disease. The results for five patients were consistent with a two compartment open model. Peak plasma concentrations were observed within 2 h following drug administration with a mean value of 0.92 micrograms/ml being recorded. The drug was rapidly eliminated as unmetabolised tiapride in the urine, 51% of the dose was recovered in 24 h. The plasma elimination half-life was 5.3 h and the average apparent plasma clearance was 16.6 l/h.

Administration, Oral↗
PubMed1985

Analysis of emissions collected from four types of iron casting molds.

The levels of polycyclic aromatic hydrocarbons (PAH) and related compounds, phenols and particulates were determined in emissions collected from iron casting molds composed of four different types of chemical binders: furan, urethane, green sand with sea coal and phenol-formaldehyde resins in shell molds. The shell sample, with 50% particulates, contained the most water-soluble material; green sand, 25% particulates; furan, 10% particulates; and urethane, less than 2% particulate material. The portion of the particulate fraction soluble in cyclohexane varies from 16 to 36% between mold types; emissions from urethane and furan molds contained the lowest quantities of cyclohexane-soluble components and of PAH and related compounds. Phenol, which was found in all four foundry samples, was present in the highest concentration in emissions from urethane molds. Shell mold emissions contained the highest levels of 2- and 4-nitrophenol.

Air Pollutants, Occupational↗
PubMed1979

Infusion rates from different containers. A study of the influence of different types of container on intravenous infusion.

Different types of containers were investigated under standardised conditions to determine whether their design affected the rate of flow of the intravenous solution they contained. Fully collapsible plastic containers were found to empty fastest, with bottles intermediate, while semi-rigid plastic containers were slowest, particularly over the last 20% of their contents. Low flow rates were found to coincide with a high sub-atmospheric pressure within the container, being greatest in the semi-rigid containers and least in the fully collapsible containers. It is suggested, therefore, that resuscitation fluids should be supplied in fully collapsible containers which have an inherent tendency to rapid infusion.

Air Pressure↗
PubMed1978

Nitrogen-containing compounds in foundry mold emissions.

Nitrogen compounds have been identified in the decomposition products from several commonly used foundry sand binders. These compounds include nitrogen oxides, hydrogen cyanide, ammonia, simple aromatic amines, and isocyanates. The concentrations of these compounds in foundry mold emissions do not appear to be directly related to the nitrogen content of the organic binders. Measurable concentrations were observed in some cases, indicating the necessity for periodic, monitoring in the foundry. Adequate ventilation will permit the use of these binders. The substitution of nitrogen-free binders suggests another possible control strategy.

Air Pollutants↗