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Biomedical subjects

R H Jago

Publications and source records attributed to R H Jago.

At least 19 recordsLinked to original sources
PubMed1996

Comparison of propofol versus thiopentone with midazolam or lidocaine to facilitate laryngeal mask insertion.

PURPOSE: To assess the ease of insertion of laryngeal mask airway (LMA) comparing propofol with lidocaine or midazolam followed by thiopentone and compare the costs with each technique. METHODS: One hundred and fifty ASA 1 or 2 patients equally divided into three groups scheduled for elective surgery were recruited into this prospective, single blind, randomized, parallel groups study. Anaesthetic induction was achieved with 1 microgram.kg-1 fentanyl i.v. followed by either 2.5 mg.kg-1 propofol (group P), or a sequence of 1.5 mg.kg-1 lidocaine and 5 mg.kg-1 thiopentone (group LT), or midazolam 0.1 mg.kg-1 and, three minutes later, 5 mg.kg-1 thiopentone (group MT). The LMA was inserted by the blinded anaesthetist who assessed and graded the conditions for LMA insertion and noted any adverse responses (i.e., inadequate jaw relaxation, gagging, coughing, limb or head movement, hiccough and laryngospasm). Conditions were considered "excellent" if there were no adverse responses, and "satisfactory" if such a response was mild and transient. RESULTS: Excellent or satisfactory conditions were observed in 48 (96%) patients in the midazolam-thiopentone group, 46 (92%) in the propofol group, and 34 (68%) in the lidocaine-thiopentone group (P = 0.0001). The incidence of gagging (P = 0.042), limb movement (P = 0.031), and laryngospasm (P = 0.0001) was higher in the lidocaine-thiopentone group. CONCLUSIONS: With the above doses, a fentanyl-midazolam-thiopentone combination which is about 35% less expensive than fentanyl-propofol, provides equally good conditions for the insertion of LMA.

Adult↗
PubMed1991

Emery-Dreifuss muscular dystrophy.

Emery-Dreifuss syndrome is a rare form of muscular dystrophy associated with cardiac complications that lead to sudden death. The disorder and its potential anaesthetic implications in the management of a patient who presented for orthopaedic surgery is described.

Achilles Tendon↗
PubMed1990

Acute viral myocarditis. A death associated with anaesthesia.

The death of a 35-year-old woman in the immediate postoperative period as a result of undiagnosed acute viral myocarditis is described. The presentation, diagnosis and course of the disease is discussed. It is recommended that wider use to be made of routine electrocardiographs as a screening test.

Acute Disease↗
PubMed1986

Spinal analgesia for transurethral prostatectomy. Comparison of plain bupivacaine and hyperbaric lignocaine.

Plain 0.5% bupivacaine and hyperbaric 5% lignocaine were compared for spinal analgesia in 100 patients undergoing transurethral prostatectomy (TURP). The time of onset, height of blockade, degree of hypotension, and blood loss were similar in both groups. The duration of blockade was considerably greater in the bupivacaine group, resulting in a significant reduction in the requirement for postoperative analgesia.

Aged↗
PubMed1984

Ketamine and military anaesthesia. The effect of heavy papaveretum premedication and Althesin induction on the incidence of emergence phenomena.

An anaesthetic technique suitable for military field anaesthesia was sought which would attenuate the psychic side effects of ketamine. Heavy premedication with 30 mg of papaveretum and induction of anaesthesia with Althesin were evaluated. A combination of the two lowered the incidence of side effects, but they still occurred frequently enough to pose problems. Ketamine sequelae are considered incompatible with the battlefield environment.

Adult↗
PubMed1983

Comparison of the frequency of muscle pain associated with suxamethonium in pre- and post-ovulatory women and in those taking a combined oral contraceptive pill.

The frequency of muscle pain following the use of suxamethonium was compared in pre- and post-ovulatory women and in those taking a combined oral contraceptive pill. There were no statistically significant differences between the groups. It is suggested that serum concentrations of progestogen were too low to produce the protection against suxamethonium pains reported in late pregnancy.

Adolescent↗
PubMed1983

Postoperative dreaming. A comparison of the incidence following pentazocine and morphine premedication.

The incidence of postoperative dreaming following the use of morphine and pentazocine as premedicants in an otherwise standard anaesthetic sequence is compared in healthy volunteers. No statistically significant difference was demonstrated between the two drugs. The causes of psychotomimetic problems in the postoperative period and the difficulty of precise definition of hallucinations are discussed.

Adolescent↗
PubMed1981

An evaluation of a pre-operative anaesthetic assessment questionnaire.

A total of 400 patients was invited to complete a pre-operative anaesthetic assessment questionnaire. On analysis 74.3% had undergone a previous general anaesthetic, 60.8% had taken some form of medication in the preceding 6 months, and 53.8% gave a significant medical history. The questionnaire is designed to focus attention on those patients at risk, to allow more efficient use of the time available for the pre-operative visit, and to provide a permanent record of the patient's medical history relevant to anaesthesia.

Adolescent↗
PubMed1977

Total intravenous anaesthesia. A technique based on alphaxalone/alphadolone and pentazocine.

Two hundred and eight patients were anaesthetised using incremental doses of intravenous alphaxalone/alphadolone (Althesin). Analgesia was provided by supplements of pentazocine, which also helped eliminate the excessive movements associated with pure Althesin anaesthesia. This is a total intravenous technique and consequently eliminates the problem of atmospheric pollution. It provides adequate anaesthesia for most minor surgical procedures.

Adolescent↗