A method for the detection of specific T4 messenger RNAs by hybridization competition.
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Acridines↗
Biomedical subjects
R H Epstein
Publications and source records attributed to R H Epstein.
Capsid size and deoxyribonucleic acid length: the petite variant of bacteriophage T4.
A mutant which produces a small-headed ("petite") variant of bacteriophage T4 is described. The mutation (E920g) maps in a new gene (66) between genes 23 and 24. Petite phage particles composed up to 70% of the phage yield. The petite phage was nonviable upon single infection but produced progeny when two or more infected a cell. Its genome was shortened by a random deletion of about 30%, and deoxyribonucleic acid (DNA) extracted from the particles was 0.68 the length of normal T4 DNA. The reduction in DNA length was accompanied by a proportional reduction in head volume. Double mutants between E920g and head-defective mutants in gene 21 produced unusually high frequencies of spherical capsidlike structures (tau-particles).
Centrifugation, Density Gradient↗
Physiologic studies in renal osteodystrophy treated by subtotal parathyroidectomy.
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Adult↗
Transcription during bacteriophage T4 development: requirements for late messenger synthesis.
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Adenine↗
Transcription during bacteriophage T4 development: synthesis and relative stability of early and late RNA.
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Coliphages↗
Electron microscopic study of the structure of mutants of bacteriophage T4D defective in tail fiber genes.
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Antigens↗
Anesthesia for cutaneous laser therapy.
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Adolescent↗