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Biomedical subjects

R Greenwald

Publications and source records attributed to R Greenwald.

31 records · Page 2Linked to original sources

Scleroderma-like fasciitis without eosinophilia after L-tryptophan ingestion.

A 53-year-old man developed severe sclerodermatous skin changes and a neuromyopathic process, consistent with the eosinophilia-myalgia syndrome, 2 months after discontinuation of L-Tryptophan (L-Try). His peripheral eosinophil count was within normal limits upon presentation and remained so throughout the illness. Currently the Centers for Disease Control surveillance definition requires peripheral eosinophilia greater than 1000 cells/mm3. Eosinophilia-myalgia syndrome may need to be part of a differential diagnosis even in the absence of peripheral eosinophilia.

Diagnosis, Differential↗

Delayed postbacteremic prosthetic joint infection.

Deep infection of a prosthetic joint is a devastating complication. One proposed mechanism of late prosthetic joint infection involves hematogenous spread from an extraarticular focus of infection. Two cases clearly demonstrate hematogenously acquired prosthetic joint infections, one caused by Clostridium perfringens and the other by Streptococcus pneumoniae. These cases were unusual in that a long asymptomatic period intervened between the primary bacteremic illness and the subsequent prosthetic infection. Patients with prosthetic joints who develop bacteremic infection at extraarticular sites should be treated promptly and aggressively with appropriate antibiotics. Prophylactic antibiotics should be strongly considered in the patient with a prosthetic joint who undergoes procedures likely to be associated with a bacteremia. Transient arthralgias at the time of bacteremia may represent the onset of the joint infection and should not be overlooked or attributed a priori to the patient's underlying arthritic or medical condition.

Aged↗

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association.

For the purposes of classification, it should be specified whether osteoarthritis (OA) of the knee is of unknown origin (idiopathic, primary) or is related to a known medical condition or event (secondary). Clinical criteria for the classification of idiopathic OA of the knee were developed through a multicenter study group. Comparison diagnoses included rheumatoid arthritis and other painful conditions of the knee, exclusive of referred or para-articular pain. Variables from the medical history, physical examination, laboratory tests, and radiographs were used to develop sets of criteria that serve different investigative purposes. In contrast to prior criteria, these proposed criteria utilize classification trees, or algorithms.

Adult↗

Rheumatoid iliopsoas bursitis presenting as unilateral leg edema.

A 66-year-old woman with rheumatoid arthritis presented with unilateral leg edema attributable to an enlarged iliopsoas bursa with presumed impedance of lymphatic drainage. The adjacent hip joint was not severely involved by arthritis. Ultrasonography and computed tomography were used to delineate the bursal mass and demonstrate communication with the joint space.

Aged↗

Endoscopic therapy of the "sump" syndrome.

Choledochoduodenostomy may be followed by the "sump syndrome." This previously required surgical intervention. We describe the successful application of endoscopic therapy in two patients with this syndrome.

Cholangitis↗

Cancer of the colon as a late sequel of pelvic irradiation.

A patient, who developed carcinoma of the rectum nine years following therapeutic radiation for pelvic malignancy is presented. The relationship of radiation to carcinoma of the colon is reviewed. This relationship makes rigorous follow-up of patients with radiation induced chronic proctocolitis essential.

Carcinoma↗

Percutaneous aspiration liver biopsy using a large-caliber disposable needle: a preliminary report.

A modification of the aspiration liver biopsy technique using a large-caliber disposable needle is described in an 18-month experience. One hundred forty liver biopsies were performed, obtaining adequate tissue in 98% of the patients. Complications occurred in 12 patients and were limited to pain at the biopsy site, epigastrium, or right shoulder; one instance of tachycardia and three of transient hypotension occurred. Thirty patients studied prospectively with liver scans and hematologic parameters failed to disclose subclinical complications. While the number of patients biopsied is still too small to provide definite conclusions , it appears that this technique is safe, similar and has a very high yield of excellent specimens. In addition, the needle offers the advantage of being disposable and easy to use by a single operator.

Adult↗

The power of suggestion: comment on EMDR and mesmerism: a comparative historical analysis.

This response to McNally challenges the notion that scientific controversy should be waged with smear tactics. McNally's anti-EMDR conclusions are contested as premature and based on red herrings, selective neglect of the literature, and erroneous application of scientific principles. The importance of treatment fidelity is highlighted as a way of distinguishing between EMDR studies of widely varying quality.

Desensitization, Psychologic↗

Effect of age on interaural asymmetry of event-related potentials in a dichotic listening task.

Three groups of subjects, children, young adults, and elderly persons with presbyacusis, were tested in a directed attention, quasidichotic paradigm in which continuous speech was monitored for syntactically and/or semantically anomalous words. The task evoked an event-related potential (ERP) characterized by a positive peak in the latency region of 600 to 1,000 msec. ERPs were separately averaged for target-word-right and target-word-left conditions. Amplitude and latency measures at the peak of the global field power waveform were calculated. Amplitude was significantly larger in children than in either adult group. In children and young adults, both amplitude and latency measures were equivalent for target-right and target-left conditions, but in elderly persons, latency was significantly greater in the target-left than in the target-right condition. Topographic maps of amplitude at the peak of the ERP waveform showed maximal positivity symmetrically distributed around the midline centroparietal area in both right-attended and left-attended conditions. In elderly persons, however, maximal positivity in the left-attended condition was significantly delayed relative to maximal positivity in the right-attended condition. Results are consistent with previous findings of interaural asymmetry in a dichotic listening task in elderly persons.

Adolescent↗

The handling of corneal donor tissue before penetrating keratoplasty.

1. Corneal tissue must meet quality standards established by Federal Regulations and state laws. 2. Documented information regarding eye bank tissue is privileged and confidential. 3. Media used to store corneal tissue must meet Food and Drug Administration (FDA) Good Manufacturing Practices standards.

Humans↗

The handling of corneal donor tissue before penetrating keratoplasty.

1. Corneal tissue must meet quality standards established by Federal Regulations and state laws. 2. Documented information regarding eye bank tissue is privileged and confidential. 3. Media used to store corneal tissue must meet Food and Drug Administration (FDA) Good Manufacturing Practices standards.

Corneal Transplantation↗