Biomedical subjects

R Graham

Publications and source records attributed to R Graham.

119 records · Page 7Linked to original sources

PubMedDate not supplied

Processing of fusion proteins with immobilized factor Xa.

Factor Xa, with a cellulose-binding domain (CBD) fused to the C-terminus of the heavy chain (FXa-CBD), is active in solution and when immobilized on cellulose. A second derivative of factor Xa in which a hexahistidine tail is fused to the C-terminus of the heavy chain (FXa-H6) also retains activity when immobilized, in this case on Ni(2+)-NTA agarose. The stabilities and activities of of FXa-CBD and FXa-H6 immobilized on cellulose and Ni(2+)-NTA agarose, respectively, are similar. Immobilized factor Xa derivatives can be used to remove affinity tags from appropriate fusion proteins without contaminating the desired product with factor Xa.

Affinity Labels↗

PubMedDate not supplied

Suppressed anger and blood pressure: the effects of race, sex, social class, obesity, and age.

We studied 572 men and women who participated in a blood pressure screening program at a government unemployment office. Before having their blood pressures taken, the subjects completed a brief questionnaire that included two items measuring conflict over anger expression. Information was also obtained on obesity, race, sex, social class, and age. Across all subjects, systolic blood pressure was found to be significantly related to suppressed anger (p less than 0.016). Normotensive were twice as likely as hypertensives to be free of suppressed anger. This relationship remained after controlling for the covariates of age, social class, and obesity. The relationship between suppressed anger and systolic blood pressure was significant for white men, exhibited a trend in black men, and was not significant for women. In contrast to the systolic findings, suppressed anger was unrelated to diastolic pressure in all the analyses.

Adult↗

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Entry of US medical school graduates into family practice residencies: 1991-1992 and 11-year summary.

This is the 11th report prepared by the American Academy of Family Physicians on the percentage of each medical school's graduates entering family practice residency programs. Approximately 10.3% of the 15,499 graduates of US medical schools between July 1990 and June 1991 were first-year residents in family practice in October 1991. This compares to 10.7% the previous year. The West North Central region reported the highest percentage of medical school graduates who were first-year residents in family practice programs in October 1991 at 15.3%; the Middle Atlantic and New England regions continued with the lowest percentages. Graduates from publicly funded medical schools were more than twice as likely as those from privately funded schools to be first-year residents in family practice in October 1991, 12.9% compared to 6.2%. Approximately half of medical school graduates entering their first year of family practice residency training in October 1991 selected a program in the same state as their medical schools. This report includes the average percentage for each medical school for the last 11 years, as well as the number and percentage of graduates from osteopathic schools who entered ACGME-accredited family practice residency programs.

Family Practice↗

PubMedDate not supplied

Results of the 1992 National Resident Matching Program.

After 4 years of declining fill rates through the National Resident Matching Program (NRMP), 74 more positions in family practice residencies were filled in 1992 than in 1991, including 24 more filled with US seniors. The March fill rate (67.5%) increased for the first time since 1987, while the July fill rate (90.7%) increased for the first time since 1984. The Mountain and Pacific regions had the highest fill rates (89.1% and 88.5%, respectively) through the NRMP. Community-based, unaffiliated and university-affiliated programs filled 71.0% and 70.3% of positions offered through the NRMP. University-based and community-based, university administered programs filled 63.8% and 61.0% of positions offered through the NRMP. The other commonly defined primary care specialties of internal medicine and pediatrics also filled increased numbers of positions offered through the NRMP. This is the first year since 1984 in which all three primary care specialties matched more positions than in the previous year. The demand for family physicians in the United States is increasing. Evidence presented here suggests that 1992 may mark the beginning of a new trend toward increased interest in careers in family practice.

Family Practice↗

PubMedDate not supplied

Entry of US medical school graduates into family practice residencies: 1990-1991 and ten-year summary.

This is the tenth report prepared by the American Academy of Family Physicians on the percentage of each medical school's graduates who entered family practice residency programs. Approximately 10.7% of the 15,433 graduates of United States medical schools between July 1989 and June 1990 were first-year residents in family practice in October 1990. This compares to 10.8% in the previous year. The Mountain region reported the highest percentage of medical school graduates who were first-year residents in family practice programs in October 1990; the Middle Atlantic and New England regions continued with the lowest percentages. Medical school graduates from publicly funded medical schools were nearly twice as likely to be first-year residents in family practice in October 1990 as were graduates from privately funded schools. The percentages for each medical school have varied substantially from year to year in the 10 years that the AAFP has reported this information. The average percentage for each medical school for the last 10 years, as well as the cumulative percentage for each medical school, are reported.

Career Choice↗

PubMedDate not supplied

Entry of US medical school graduates into family practice residencies: 1989-1990 and nine-year summary.

This is the ninth report prepared by the American Academy of Family Physicians on the percentage of each medical school's graduates who entered family practice residency programs. Approximately 10.8% of the 15,646 graduates of United States medical schools between July 1988 and June 1989 were first-year residents in family practice in October 1989. This compares to 10.7% in the previous year. The West North Central region reported the highest percentage of medical school graduates who are first-year residents in family practice programs in October 1989; the Middle Atlantic and New England regions continued with the lowest percentages. Medical school graduates from publicly funded medical schools were twice as likely to be first-year residents in family practice in October 1989 than were graduates from privately funded schools. The percentages for each medical school have varied substantially from year to year in the nine years that the AAFP has reported this information. The average percentage for each medical school for the last nine years, as well as the cumulative percentage for each medical school, are reported.

Family Practice↗

PubMedDate not supplied

Entry of U.S. medical school graduates into family practice residencies: 1988-1989 and eight-year summary.

This study continues a series of reports from the American Academy of Family Physicians on the percentage of each medical school's graduates who enter family practice residency programs. Approximately 10.7% of the 15,947 graduates of United States medical schools between July 1987 and June 1988 were first-year residents in family practice in October 1988. This compares to 12.0% in the previous year. The Mountain region reported the highest percentage of medical school graduates who are first-year residents in family practice programs in October 1988; the Middle Atlantic and New England regions had the lowest percentages. Medical school graduates from publicly funded medical schools were twice as likely to be first-year residents in family practice in October 1988 as were graduates from privately funded medical schools. The percentages for each medical school have varied substantially from year to year in the eight years that the AAFP has reported this information. The average percentage for each medical school for the last eight years, as well as the cumulative percentage for each medical school, are reported. Although school-specific percentages may show wide year-to-year variations, the total percentage of U.S. medical school graduates entering family practice residencies has been generally stable near 12.0% in the previous seven years. The decline to 10.7% for 1987-88 is cause for careful review.

Career Choice↗

PubMedDate not supplied