Search PubMed⌕ Search

Biomedical subjects

R Gothe

Publications and source records attributed to R Gothe.

At least 91 records · Page 5Linked to original sources
PubMed1991

[Babesiosis of dogs in Germany: epidemiologic case analysis].

Between January 1987 and February 1990 Babesia infections were detected in 320 dogs in Germany by means of microscopical and/or serological methods. It was found, that 316 dogs were infected with Babesia canis and 4 animals with Babesia gibsoni. Of the Babesia-canis-positive dogs 184 were abroad up to 4 months before diagnosis, mainly in France, Spain and Italy, but also in Hungary, Greece, Jugoslavia, Portugal, Morocco, Togo, Pakistan, Sri Lanka, Malaysia, Turkey, Romania, Austria and the Netherlands. For further 36 dogs the possible place of infection for Babesia canis could not be clarified geographically. 5 dogs each were simultaneously infested with Rhipicephalus sanguineus and Dermacentor reticulatus, respectively. The four dogs infected with Babesia gibsoni were previously in Sri Lanka (2), Brazil (1) or Algeria/Kenya (1). In 88 dogs from the Offenburg/Lahr/Freiburg area, which were not abroad, infections with Babesia canis were diagnosed from January to June as well as from September to December, however, most cases occurring in April and May. Of these dogs approximately 20% were found to be infested with Dermacentor reticulatus. These ticks were also collected on the vegetation in the Offenburg area. Therefore, an endemic focus of Babesia canis can be deduced in the area of Offenburg/Lahr/Freiburg and Dermacentor reticulatus as vector also in Germany.

Animals↗
PubMed1990

On the morphology and organization of the eye of unfed adult Rhipicephalus evertsi mimeticus (Acari: Ixodidae).

Investigations by scanning and transmission electron microscopy and freeze-etching revealed that eyes of adult Rhipicephalus evertsi mimeticus consist of a lens and photoreceptor cells, which are separated by an acellular layer and the hypodermis. The lens contains numerous pore channels, which open beneath the epicuticula of the outer portion, converge uninterrupted to the inner closure and end in approximately 420 pore fields. The inner closure of the lens is formed as a deep circular invagination. Beneath the hypodermis and perpendicular to the lens, a group of approximately 20 highly differentiated photoreceptor cells in a rosette-like arrangement is localized within the invagination of the lens. Each photoreceptor cell is characterized terminally by numerous, tightly packed and parallel-running microvilli, which are oriented perpendicularly to the lenticular pore channels.

Animals↗
PubMed1990

Eimeria infections of sheep in northwest Germany.

To investigate the incidence of ovine Eimeria spp. and seasonal dynamics in oocyst output, fecal samples of sheep from three different management systems were collected monthly over a 1-year period and examined for oocysts. A total of 10 species of Eimeria were observed. The most frequent species were E. bakuensis, E. ovinoidalis, E. weybridgensis/crandallis, E. parva and E. ahsata whereas E. faurei, E. granulosa, E. intricata and E. pallida were found less often. Lambs passed larger numbers of oocysts in their feces than either ewes or yearlings.

Animals↗
PubMed1990

[The frequency of coccidial infection in dog families of different husbandry and breeds in south Germany].

Oocysts and/or sporocysts were detected in 50 litters and 37 bitches of 100 coproscopically examined dog families in Southern Germany. Oocysts of Isospora spp. were excreted by 41 of the 50 positive litters, 36 and 16 litters shedding oocysts of Isospora ohioensis/burrowsi and I. canis, respectively. Sporocysts of Sarcocystis spp. and oocysts of Hammondia heydorni were detected in 12 and 7 litters, respectively. The excretion rates of the dams were arranged analogous to the detection of oocysts of Isospora spp. in 25 animals. Sporocysts of Sarcocystis and oocysts of H. heydorni were excreted by 19 and 6 dams, respectively. With regard to husbandry conditions distinct differences were established only for Isospora spp., because dog families kept in kennels always revealed higher excretion levels than dog mothers and their litters kept indoors. Excretion intensities increased directly proportional to the number of additional adult dogs and the number of litters born per year/stock, reaching maximum values of 80-100%. Analysis revealed no breed-related differences.

Animal Husbandry↗
PubMed1990

The detection and isolation of a paralysis toxin present in Argas (Persicargas) walkerae.

One-day-old leghorn chickens were used in a laboratory assay to determine the toxicity of crude extracts of the tick Argas (Persicargas) walkerae and of fractions obtained during the isolation procedure. Extracts of unfed and engorged larvae, nymphae and females were tested using this in vivo test system. Only extracts of replete A. (P.) walkerae larvae produced paralysis. A toxic fraction was isolated from replete larval extracts by gel-permeation and ion-exchange chromatography. This fraction with a pI of 4,5, showed 2 major bands corresponding to a Mr of 32 kDa and 60 kDa after SDS-polyacrylamide gel electrophoresis.

Animals↗
PubMed1990

[Helminth infections in wild boars in enclosures in southern Germany: species spectrum and infection frequency].

To determine the helminth fauna of wild boars, stomachs and intestines of 124, lungs of 62, and livers of 39 animals from 5 enclosures in Southern Germany were examined. The evaluation of the species composition revealed at least 13 species: Metastrongylus apri, M. salmi, M. pudendotectus, Physocephalus sexalatus, Hyostrongylus rubidus, Globocephalus longemucronatus, Ascaris suum, Trichuris suis, Oesophagostomum dentatum, O. quadrispinulatum, Fasciola hepatica, C. tenuicollis and Capillaria. The most frequently isolated species was M. salmi with 91.9%, followed by G. longemucronatus with 91.1%, M. apri with 88.7%, M. pudendotectus with 87.1%, P. sexalatus with 51.6%, O. dentatum with 46%, T. suis with 30.6%, H. rubidus with 14.5%, A. suum with 12.1% and O. quadrispinulatum with 8.1%. Differences in the prevalence of infection, determined for animals up to 1 year old, 1-2 year-old and adults, were minimal for Metastrongylus spp. and G. longemucronatus. P. sexalatus, T. suis and A. suum, however, occurred more often in 1 year old, whereas H. rubidus, O. dentatum and O. quadrispinulatum were isolated more often from adults. A correlation of the infection rate with the sex of the animals was not found.

Animals↗
PubMed1990

[Spectrum of species and infection frequency of endoparasites in bitches and their puppies in south Germany].

Toxocara canis, Toxascaris leonina, hookworms, Trichuris vulpis, Strongyloides, Hammondia heydorni, Sarcocystis spp., Isospora canis and Isospora ohioensis and/or Isospora burrowsi of at least 9 species were detected in 100 randomly selected dog families in Southern Germany. Examinations carried out 5 to 9 times at weekly intervals revealed a monoinfection in 37 litters, infection with two parasite species in 28 litters, with three species in 10 litters and with four species in 6 litters. During the investigation period, 29 of the examined litters did not excrete helminth eggs, and, of these, 19 also did not excrete oocysts/sporocysts. In order of decreasing frequency among the dog families, the excretion extent of the litters and their mothers was as follows: Toxocara canis 67% and 45%, Isospora ohioensis/burrowsi 36% and 24%, Sarcocystis spp. 12% and 19%, Isospora canis 16% and 8%, Hammondia heydorni 7% and 6%, hookworms 6% and 7% and Toxascaris leonina 3% and 8%, respectively. Trichuris vulpis and Strongyloides eggs were only detected in 6 and 3 of the bitches, respectively.

Animals↗
PubMed1990

[Toxocara canis: frequency of detection and extent of infection in bitches of various breeds and husbandry and their litters in South Germany].

Epidemiological investigations of 100 randomly selected dog families in Southern Germany revealed eggs of Toxocara canis in 67% of the litters and in 45% of the bitches. Eggs were isolated from litters at the earliest on the 16th day and at the latest on the 55th day post partum, in bitches on the 19th and 60th day respectively after giving birth. With regard to the coproscopically detected frequency of T. canis eggs in separate analyses of the dog breeds, only slight differences were found; very large breeds, however, revealed substantially a greater excretion extent. An evaluation exclusively concerned with the way the dog families were kept showed a higher percentage of 76.2% for litters from kennels than among those kept indoors, which amounted only to 51.4%. Relating the excretion extent to the number of additionally kept fully grown dogs/breeder, evident correlations were found, as the number of positive litters increased together with the number of additionally kept adult dogs/dog family. In comparison with dog families exclusively kept indoors, kennel dogs had a higher extent of excretion. Regarding the number of litters born per year/stock compared with excretion extent a positive correlation could be drawn for dog families up to 5 litters/year only. The number of litters born per bitch had no influence on the excretion extent of the litters. Correlations between the number of anthelminthic treatments of litters or bitches during and following pregnancy and the excretion extent of T. canis could not be deduced. The litters remained positive even after 5-8 treatments during the investigation period of 9 weeks and positive results continued after the puppies had been sold.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1989

[Demodicosis of dogs--a factorial disease?].

Demodex canis is a normal resident of the intact canine skin, being present in small numbers in virtually every dog. Most animals are only carriers of the mites and do not develop clinical symptoms, therefore, demodectic mange has already to be considered as a factorial disease. The modus operandi of transition of clinically inapparent colonization of the mites into a disease may be explained according to investigations so far published multifactorially and thereby essentially as consequences of primary or secondary immunodepression. A primary immunodepression is initially based most probably on a hereditary defect of T-cells and is subsequently reinforced by substances, which are presumably synthesized and liberated not only by mites but also by secondary bacterial agents. A secondary immunodepression operates as trigger mechanism of a clinical manifestation after corticosteroid or cytostatic therapy or in course of underlying diseases of potentially immunodepressive nature, i.e., malignant neoplasia, hepatopathies, hyperadrenocorticism and lymphosarcoma.

Animals↗
PubMed1989

[Sensitivity of Argas (Persicargas) walkerae to optic irradiation and localization and organization of light perceiving or permeability areas of the integument].

Considering a negative phototaxis as a stimulus reaction to narrow - or wideband monochromatic radiance of varying ranges of wavelengths and different irradiance it was established that both unfed and engorged I. and II. nymphs, as well as male and female adult ticks of Argas (Persicargas) walkerae, responded almost to the whole spectrum of the investigated wavelengths from 246-809nm, however, depending on the irradiance. Peaks of sensitivity with 50-100% of phototactically negative reacting ticks, however, were only registered in the range of 415 nm to 604 nm at moderate and high irradiance. Interstadially unfed and fed ticks showed no or only slight differences of reaction. Engorged ticks responded analogously to the unfed ticks but usually with smaller percentages. The lower readiness of reaction of the engorged stages was also established by the comparison of the temporal threshold values, which were ca. 1 min shorter for unfed ticks. Ablation tests for localizing light perception in or through the integument by means of covering the integumental areas in various combinations and simultaneously confronting them with the highly sensitive range of wavelengths from 446-568 nm revealed that unfed female adults probably perceived the light stimuli primarily through the dorsum. Covering the entire dorsum with white or black paint caused a phototactically negative response in 10-30% of the ticks. Untreated control ticks reacted to the light stimuli with a proportion of 50-75%. Scanning electron microscopical examinations of the dorsum, ventral surface and supracoxal folds of unfed female ticks gave no evidence of morphologically recognizable, superficially organized or integument-integrated photoreceptor areas or optical organs similar to lenses.

Animals↗
PubMed1987

Histology and ultrastructure of the glands associated with the porose areas on the gnathosoma of Rhipicephalus evertsi evertsi before and during oviposition.

Histological and electronmicroscopical studies have shown that the subcuticular tissue associated with the porose areas of female Rhipicephalus evertsi evertsi consists of paired multicellular, alveolar and lobularly arranged glands. At least two types of cells are clearly distinguishable, according with their location. Proximally, in direct association with the pores, cells with small and long nuclei are present. These cells are aligned along large, elongated lumina containing numerous microvilli and extend deep into the cuticular pores. They are separated from the extraintegumental space by cuticular valves. The distal gland sections are characterized by cells with large nuclei which are mostly arranged in the form of rosettes. These cells, which function as secretory cells, contain many mitochondria, smooth and rough endoplasmic reticulum and membrane-lined vesicles. The glands are always present in female ticks and their dorso-ventral extension increases continuously with feeding, reaching a maximum depth during oviposition.

Animals↗
PubMed1987

[Sarcoptic mange of dogs: biology of the organism, epidemiology, pathogenesis, clinical aspect, diagnosis and treatment].

A review is presented on the biology of the causative agent, epidemiology, pathogenesis, clinical features, diagnosis and therapy of canine Sarcoptes scabiei infestation. This survey includes also clinical data of the period 1978-1986 in the Small Animal Hospital, Munich Veterinary Faculty. Several skin scrapings are usually necessary for diagnosis. For therapy application of acaricides once a week, altogether at least three times is sufficient. Simultaneously a decontamination of the dog's surroundings should be carried out.

Animals↗
PubMed1987

Tick pheromones.

According to their activity profiles tick pheromones can be characterized as assembly pheromones, aggregation/attachment pheromones, pre-attachment or pre-feeding pheromones, attractant sex pheromones, contact sex pheromones, fecundity-reducing pheromone and various ungrouped pheromones. This paper gives a short review of the chemical characteristics, biological roles, and activity periods as well as the sites of production and release of tick pheromones.

Animals↗