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Biomedical subjects

R Gordon

Publications and source records attributed to R Gordon.

At least 289 records · Page 16Linked to original sources

A capillarity mechanism for diatom gliding locomotion.

It is proposed that the diatom raphe is a parallel-plate capillary containing a fluid which reacts at the trailing end, turning into a form which no longer "wets" the raphe walls, and which is left behind as a trail. More unreacted raphe fluid is drawn by capillary pressure from a source near the leading end of the raphe. This fluid sticks out from the raphe along its length, adhering to surfaces, thus causing gliding locomotion. Formulae are given for the maximum velocity and force of a moving diatom in terms of the raphe dimensions and the surface tension and viscosity of the fluid. An a priori estimate of the force exerted by a moving diatom, 1-50 millidynes, agrees with measured values. Five experimental tests of the theory are proposed.

Journal Article↗

p-Chlorophenylalanine-induced chemical manifestations of phenylketonuria in rats.

p-Chlorophenylalanine, a potent inhibitor of phenylalanine hydroxylase in vivo, has been used to simulate phenylketonuria in rats. This inhibitor, when administered with phenylalanine, produces marked elevation of blood and tissue phenylalanine without an increase in tyrosine. Disproportionate ratios of phenylalanine to tyrosine are characteristic of phenylketonuria in humans. The use of p-chlorophenylalanine permits the production of this characteristics amino acid imbalance in experimental animals.

Animals↗