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Biomedical subjects

R Gongora

Publications and source records attributed to R Gongora.

28 records · Page 2Linked to original sources
PubMed1980

[Carcinoma of the breast: diagnosis of sub-clinical bone metastases. Predictive value of isotope bone scan (author's transl)].

The possibility of drawing a distinction between two groups with or without bone metastases is of fundamental importance in the determintion of management. With this in mind, isotope bone scan using Tc 99 was performed routinely in 99 cases of locally advanced non-metastatic carcinoma of the breast. Amongst 121 "operable" (T1, T2, T3, N0, N1a) carcinomas, 4 (3%) had a positive scan. Of these 4 cases, 3 showed evidence of bone metastases within one year, in 3 of which the site was not the same as that predicted by the scan. Amongst 53 "inoperable" (T4, N0, N1, T., N2, N3) cases, 5 (10%) had a positive scan and 5 a doubtful scan. Amongst the 5 positive cases, within one year metastases were seen at the predicted site. In agreement with a large number of authors, it would thus appear that routine isotope bone scan has no role to play in the pretherapeutic assessment of so-called "operative" breast carcinomas.

Bone Neoplasms↗
PubMed1979

[Tracheo-bronchial and pulmonary depositions as measured by radioactive tracers. Study on healthy and pathological subjects (author's transl)].

The result of a study done on 52 subjects including a thorough ventilatory functional test and the radioisotopic measurement of inhaled particles deposition, by working out the TB/P ratio, revealed that: 1. giving aerosol needs an exacting technique when used for quantitative aims; 2. ratio TB/P is increased in patients with chronic broncho-pulmonary diseases, because of a predominantly tracheo-bronchial deposition of particles; 3. in patients with a satisfactory ventilatory function the TB/P ratio is increased; on the other hand in patients with ventilatory disorders, the ratio is normal. The repartition of particles deposition between the compartments TB and B depends therefore not only on factors involving ventilatory functional values but also on the physiopathological factors not included in them.

Bronchi↗
PubMed1978

[Serum beta2-microglobulin and carcino-embryonic antigen in cancerous patients. A preliminary study of 258 cases (author's transl)].

In this preliminary study dealing with beta2-microglobulin (beta2m) levels in the series of 258 patients, two group are considered:--a group of 208 patients with evolutive tumour;--a group of 50 patients with no evolutive tumour. This study shows a significantly higher incidence of cases with elevated levels of carcinoembryonic antigen (CEA) and/or beta2m in group with evolutive cancer than in group with no evolutive cases. These elevated levels of beta2m are not related to other clinical, topographical, evolutive, immunological parameters. But the increase of serum beta2m levels in patients treated with combination of chemo and immunotherapy, may indicate a possible relationship between beta2m levels and lymphocyte activation.

Beta-Globulins↗