Clinicopathological conference. Pelvic mass in a 37-year-old man.
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Biomedical subjects
Publications and source records attributed to R Golden.
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Amyloidosis has not been included in the wide spectrum of medical complications associated with drug abuse. Chronic visceral infection is a recognized cause of amyloidosis, but chronic suppuration of the skin is not a well-appreciated cause of this condition. Furthermore, to our knowledge, chronic skin suppuration secondary to parenteral drug abuse has not been reported as a cause for systemic amyloidosis. We report a case in which subcutaneous injections of narcotic tablets led to chronic skin suppuration and systemic amyloidosis.
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Output-area factors are usually provided only for square fields at one standard distance. To calculate dose for mantle, extended field, total nodal, subtotal body, and total body irradiation, output-area factors are required for a continuous range of shapes and distances. Dose rate measurements have been made for different elongation ratios at various distances with an Allis-Chalmers 25-MV betatron, an AECL Theratron-80 60Co unit, a Picker C-9 60Co unit, and a Picker C-10000 60Co unit. A model is presented that permits the extension of dose rates and area factors for square fields at one distance to elongated fields at any distance. An illustrative calculation for one of the units is given.
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