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Biomedical subjects

R Gergely

Publications and source records attributed to R Gergely.

6 recordsLinked to original sources
PubMed1999

An evaluation of the effectiveness of lead paint hazard reduction when conducted by homeowners and landlords.

This research project was conducted in collaboration with the Iowa Department of Public Health to evaluate whether property owners who follow recommended procedures for lead-based paint removal/repair can do the work safely and effectively. This study included 29 homes where a lead-based paint hazard had been identified and lead-based paint was removed or repaired (hazard reduction). Exposure evaluation included pre-project surface dust wipe sampling, air monitoring during lead-based paint removal, post-project surface dust wipe sampling, and pre- and post-project blood samples from adult study participants. The comparison of surface dust wipe samples taken before and after lead paint hazard reduction was used to evaluate the effectiveness of lead paint hazard reduction. The lead loadings on window sill surfaces in the work area were significantly lower after completion of the project (p = 0.04), and the lead-based paint removal did not contaminate the adjoining living area. The proportion of homes with surface dust lead loading exceeding Department of Housing and Urban Development (HUD) clearance standard was 73 percent pre-project and 38 percent post-project. Personal airborne exposures during lead removal activities (geometric mean = 59.3 micrograms/m3) reinforce the need for respiratory protection and good hygiene. There was no difference in adult pre-/post-blood levels, indicating that participants did remove lead in a safe manner with respect to their own exposures. The results indicate that hazard reduction can be done effectively when recommended procedures for the removal of lead-based paint are followed.

Adult↗
PubMed1978

Oral contraceptives and focal nodular hyperplasia of the liver. Two case reports with electron-microscopic studies.

The authors report on the cases of 2 young females who had been on oral contraceptives for 2 and 6 years, respectively. During cholecystectomy, as a subsidiary finding, liver tumour was found which, histologically, proved to be focal nodular hyperplasia. On the basis of their electron-microscopic studies, they consider possible the primary role of pathological vascularization in the development of the tumour. They suggest the radical removal of the tumour and regard as inevitable for the patient the stopping of oral contraceptives, due to the recurrence or malignant transformation of the tumour.

Basement Membrane↗
PubMed1977

[Primary carcinoma of the liver and long-term administration of oral contraceptives followed by pregnancy (author's transl)].

A 32-year-old woman who had taken oral contraceptives for seven years, became pregnant after omitting the drug and had a normal child. Soon after a malignant hepatic tumour became apparent of which she died after three months. The tumour was a hepatocellular carcinoma, of low differentiation under the electron microscope. The tumour cells contained fibrils similar to alcoholic hyaline. A review of published reports suggests the possibility that the oral contraceptives and the hormonal influence of the pregnancy together played an important role in the development of the malignant tumour.

Adult↗