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Biomedical subjects

R Garg

Publications and source records attributed to R Garg.

103 records · Page 6Linked to original sources

Auditory brain stem evoked response in normal neonates and infants.

Auditory brainstem evoked responses (ABER) were recorded to provide normative data regarding the latency values, brainstem conduction times in term neonates and infants up to 24 months of age. The mean latency for wave I - 1.86 +/- 0.11 m sec, wave III - 5.11 +/- 0.31 m sec, wave V - 7.10 +/- 0.30 m sec progressively decreased at birth to wave I - 1.64 +/- 0.17 m sec, wave III - 4.40 +/- 0.27 m sec, wave V - 6.15 +/- 0.21 m sec at 12 months of age by stimulus strength of 75 decibels at a rate 20 clicks/sec. Interwave conduction times improved to I-III - 2.76 +/- 0.29 m sec, I-V - 4.51 +/- 0.29 m sec, III-V - 1.75 +/- 0.17 m sec at 12 months from I-III - 3.25 +/- 0.26 m sec, I-V - 5.23 +/- 0.23 m sec, III-V - 1.99 +/- 0.35 m sec at birth.

Evoked Potentials, Auditory↗

Adreno-cortical function in leprosy.

Adreno cortical function was carried out in 43 cases of leprosy. These cases were further divided into tuberculoid, borderline, lepromatous and Lepra reaction. Serum and urinary electrolyte, urinary 17-Ketosteroid and 17-Ketogenic steroid and plasma cortisol levels were measured to assess the adrenocortical status in these different forms of leprosy. It was observed that these parameters were within normal limit in tuberculoid leprosy except low value of urinary 17-Ketogenic steroid. The borderline and Lepromatous leprosy cases revealed low values of urinary sodium, potassium and 17-Ketogenic steroid and high level of serum potassium. However, the cases of lepra reaction revealed low value of serum and urinary sodium and potassium, urinary 17-Ketogenic steroid. The basal plasma cortisol level was high in this group but it was statistically insignificant.

17-Ketosteroids↗

Cardiac glycosides in the next millennium.

Despite the documented efficacy of cardiac glycosides in improving symptoms in patients with heart failure caused by systolic ventricular dysfunction, considerable debate continues as to whether the use of this class of drugs should continue into the next millennium. In this review, the authors briefly examine the basic pharmacology of these drugs relevant to the treatment of heart failure, emphasizing their role in reducing sympathetic nervous system activity in patients with advanced heart failure. Next, withdrawal trials and the Digoxin Investigation Group dataset are reviewed in some detail. Despite these important additional data on the safety and efficacy of digitalis use in heart failure that became available in the 1990s, considerable controversy remains. Perhaps most importantly, if the mechanism by which these drugs improve symptoms in patients with heart failure is principally mediated by sympatholytic activity, do they remain relevant as beta-adrenergic antagonists become standard therapy for this disease?

Cardiac Glycosides↗

Thyroid function in leprosy.

Thyroid function tests were carried out in 43 cases of leprosy. The study subjects included cases of tuberculoid, borderline and lepromatous leprosy and those with lepra reaction. The parameters studied included serum cholesterol, protein bound Iodine, serum T3 level and serum T4 levels. The levels of serum cholesterol and protein bound Iodine were normal in all the four groups of leprosy patients. However, the mean serum T3 and T4 were low in all the four groups. The difference in the levels of serum T3 was statistically significant only in the lepra reaction group. The levels of T4 were statistically significantly decreased in borderline leprosy, lepromatous leprosy and in lepra reaction.

Adolescent↗

Glucose tolerance test in leprosy.

Glucose tolerance test was carried out in 43 cases of leprosy. They included cases of tuberculoid, borderline, lepromatous leprosy and those with lepra reaction. It was observed that normal curve was common in tuberculoid leprosy. Flat glucose tolerance curve was observed in borderline and lepromatous leprosy. However, the diabetic curve was common in Lepra reaction. Fasting blood sugar was low in lepromatous leprosy and it tended to be marginally high in lepra reaction. Normal GTT response was observed in those with duration of disease between 0-6 months, flat curves in those with duration of disease between 7-12 months while diabetic curve was more common in those with disease duration of more than 2 years.

Adolescent↗