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Biomedical subjects

R G Wells

Publications and source records attributed to R G Wells.

99 records · Page 6Linked to original sources

Parapharyngeal soft-tissue infection with Aeromonas hydrophila.

Parapharyngeal soft tissue infections may be rapidly progressive and life-threatening. Prompt institution of appropriate antimicrobial therapy is of paramount importance. This report highlights the potential virulence of Aeromonas hydrophila in infection of the head and neck and the need to consider this organism in selected patients.

Adult↗

Hemimegalencephaly: clinical, EEG, neuroimaging, and IMP-SPECT correlation.

Iofetamine-single photon emission computed tomography (IMP-SPECT) was performed on 2 girls (5 1/2 and 6 years of age) with histories of intractable seizures, developmental delay, and unilateral hemiparesis secondary to hemimegalencephaly. Electroencephalography (EEG) revealed frequent focal discharges in 1 patient, while a nearly continuous burst suppression pattern over the malformed hemisphere was recorded in the other. IMP-SPECT demonstrated a good correlation with neuroimaging studies. In spite of the different EEG patterns, which had been proposed to predict contrasting clinical outcomes, both IMP-SPECT scans disclosed a similar decrease in tracer uptake in the malformed hemisphere. These results are consistent with the pattern of decreased tracer uptake found in other interictal studies of focal seizures without cerebral malformations. In view of recent recommendations for hemispherectomy in these patients, we suggest that the IMP-SPECT scan be used to compliment EEG as a method to define the extent of abnormality which may be more relevant to long-term prognosis than EEG alone.

Amphetamines↗

CT findings in noma.

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Child, Preschool↗

Sequelae of temporal lobe herniation: MR imaging.

Acute temporal lobe herniation is a serious complication that may occur with an expanding temporal or parietal lobe mass. Temporal lobe herniation may produce further damage to intracranial structures due to compression or vascular compromise. Differentiation of clinical and imaging abnormalities due to the primary lesion from those related to temporal lobe herniation is essential for proper diagnosis and management. The CT and magnetic resonance findings in a 2 1/2-year-old child who survived severe temporal lobe herniation are reported.

Brain Neoplasms↗

MR features of fleeting CNS lesions associated with Epstein-Barr virus infection.

The magnetic resonance and CT findings in a 10-year-old patient with neurologic abnormalities associated with Epstein-Barr virus infection are reported. Multiple focal lesions of various sizes were demonstrated with involvement at one time or another of both cerebral hemispheres, the right thalamus, the right cerebellar hemisphere, and the right optic nerve. A unique finding was the fleeting nature of the lesions with new lesions appearing as others resolved. The clinical presentation, laboratory studies, and radiologic patterns suggest the diagnosis of immune-related acute disseminated encephalomyelitis associated with Epstein-Barr virus infection.

Brain↗

Nocardia choroid plexitis: CT and MR findings.

We report a case of nocardia choroid plexitis with extension into the parenchyma of the left parietal lobe in a previously well 13-year-old girl. The neuroimaging findings mimicked those of an intracranial neoplasm. This case illustrates the importance of including infectious etiologies in the differential diagnosis of aggressive choroid plexus lesions. The differential diagnosis of enhancing lesions of the choroid plexus in children is discussed.

Adolescent↗