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Biomedical subjects

R G Taylor

Publications and source records attributed to R G Taylor.

At least 145 records · Page 8Linked to original sources
PubMed1975

Dislocation and fracture-dislocation of the pelvis.

Dislocation and fracture-dislocation of the pelvis is a major injury; the force involved in its production may not only disrupt the pelvis but result in extensive associated injuries. Between 1960 and 1968, 43 patients with this injury were treated in the Accident Service of the Radcliffe Infirmary. Their case records and radiography have been analysed and 29 of the patients re-assessed at a follow-up examination.

Adolescent↗
PubMed1975

Incidence of acetylcholinesterase in the sarcoplasm of human and chicken muscles.

Fifty-nine biopsies of human muscle, 53 of them abnormal, 6 normal, were studied for the histochemical localization of acetylcholinesterase (AChE) using frozen sections and light microscopy. In addition to AChE which was found at the myoneural and myotendon junction, specific staining was found around the periphery of many fibers from normal and abnormal muscles. Moreover, AChE activity was found to be high in the sarcoplasm of more than 10% of the fibers from 28 biopsies of abnormal muscle including cases of hemiplegia, spinal cord injury, denervation and neuropathy, infantile spinal muscle atrophy, Duchenne, limb-girdle and facioscapulohumeral dystrophies, Schwartz-Jampel syndrome and a myasthenic syndrome. Of the muscles from experimental animals examined, only the Rhesus monkey exhibited AChE around the periphery of the fibers, and only the dystrophic chicken and not the dystrophic mouse or hamster, showed extensive sarcoplasmic AChE. Histograms of muscle fiber diameters indicated that AChE in the sarcoplasm was associated with fibers of all sizes, depending on the nature of the disorder examined. Fibers containing AChE were smaller than unstained fibers in dystrophic chicken muscle. The results suggest that in the human, sarcoplasmic AChE is reversibly repressed during muscle maturation and that its mode of regulation by motor neurons is similar to that found in the chicken.

Acetylcholinesterase↗
PubMed1975

Cervical spine injury in patients with ankylosing spondylitis.

Fractures of the cervical spine associated with ankylosing spondylitis are rare. Relatively minor injury can cause a fracture of the vertebral body or through the ossified intervertebral space, because of the loss of normal flexibility, mobility, and elasticity in the rigid spine. Sixty-six per cent of the fracture subluxations of the ankylosed spine are associated with injury to the spinal cord, and the mortality rate is 40%. Because of the complete nature of fracture and instability, there is a high risk of neurologic deterioration. Immobilization of the cervical spine in a Halo cast appears to be the treatment of choice. If skull traction is applied the cervical spine should be immobilized in the neutral position, and overzealous traction exceeding 10 pounds should be avoided. Callus formation and fracture healing following immobilization is rapid. Four new cases are described and 44 previously reported cases in the literature have been reviewed.

Cervical Vertebrae↗
PubMed1975

Brachial plexus root avulsion: role of myelography--review of diagnostic procedures.

Myelographic evidence of traumatic meningocele in brachial plexus injuries has been considered to be pathognomonic of root avulsion. Two such cases with myelographic evidence of root avulsion with excellent recovery at those levels are presented. Various diagnostic procedures in brachial plexus injuries are critically reviewed. The sequence in which these tests are of diagnostic value are: 1) clinical evaluation, motor and sensory, from the time of admission; 2) electroneuromyography at 2-3 weeks following injury; 3) axon reflex response at 2-3 weeks; 4) myelography; 5) very rarely, surgical exploration.

Adult↗