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Biomedical subjects

R G Moses

Publications and source records attributed to R G Moses.

At least 55 records · Page 3Linked to original sources

An evaluation and comparison of Reflolux II and Glucometer II, two new portable reflectance meters for capillary blood glucose determination.

The Reflolux II and the Glucometer II, two new battery-operated portable reflectance meters (PRMs) for blood glucose measurement have been evaluated for accuracy, precision and ease of operation. Both PRMs are pocket-size and simple to use. The calibration of the two instruments is fundamentally different, but in both cases the calibration data are provided with the reagent test strips and require minimal operator participation. The analysis time is 50 s for the Glucometer II and 120 s for the Reflolux II. The Reflolux II has a measuring range of 0.5-27.7 mmol/l, which is superior to the 2-22 mmol/l range of Glucometer II. Both PRMs had excellent correlation (r greater than 0.97) and minimal bias when compared by regression analysis to a laboratory method on capillary and whole blood samples. The precision of the Reflolux II was marginally better than the Glucometer II with coefficients of variation less than 6.57% for the Glucometer II and less than 5.21% for the Reflolux II. Neither the Reflolux II nor the Glucometer II offer significant advantages one over the other, both are adequate for their designed use, and both are distinct improvements over their predecessors.

Blood Glucose↗

Quality control of portable reflectance meter capillary blood glucose results by measurement of glucose on filter paper.

The capillary blood glucose (CBG) estimated by some of the most frequent users of portable reflectance meters (PRMs) were assessed using blood applied to Whatman 31 ET filter paper at the time of the performance of the CBG. The performance of nursing staff on hospital wards, community groups screened for diabetes and patients exercising self monitoring of blood glucose (SMBG) at home were evaluated. The glucose was extracted from the filter paper with 5% trichloroacetic acid (TCA) and analyzed within 5 days of collection on a Technicon RA-1000 analyzer using Merck glucose dehydrogenase reagents. Of the 1255 samples collected, 385 were rejected due to inadequate sample collection, and a further 196 were rejected as they were received more than 5 days after collection, the time interval allowed for glucose stability on the filter paper. The CBGs obtained by the nursing staff were 2.2 - 17.1 mmol/l with a mean of 7.6 mmol/l; the community screened subjects CBGs were 1.5 -22.4 mmol/l with a mean of 5.2 mmol/l; and the SMBG users at home obtained CBGs of 1.0 - 15.1 mmol/l with a mean of 5.07 mmol/l. Of the 674 samples analyzed only 36.6% were within 10% of the laboratory blotting paper glucose (BPG) result. An alarming 35.8% exceeded 20% and 10.2% exceeded 50% of the BPG result. The correlation of all 3 groups with the BPG obtained by the laboratory were similar (correlation coefficient = 0.86, 0.85, 0.87 respectively).(ABSTRACT TRUNCATED AT 250 WORDS)

Blood Glucose↗

Prevalence of diabetes mellitus in Australia. The establishment of a register of diabetic children aged 0 to 19 years in the Illawarra area.

A survey to establish a register of diabetic children aged 0 to 19 years has been carried out in the Illawarra area of New South Wales. Four independent methods of case ascertainment were used. Fifty-three patients with diabetes mellitus were identified, with a prevalence of the disease of 69/100 000. Ten patients with diabetes were diagnosed in 1984, giving an annual incidence of 13/100 000. No significant seasonality in onset of diabetes was demonstrated.

Adolescent↗

Severe hypoglycaemia. A one-year prospective survey in Wollongong.

A one-year prospective survey of serious hypoglycaemia has been carried out in the Wollongong area. Of insulin-treated patients attending the diabetes clinic, 3.5% had a hypoglycaemic attack of sufficient severity to be referred to hospital. A further 1% received treatment for attacks of hypoglycaemia at home. It is considered that nearly two-thirds of the attacks of hypoglycaemia may have been preventable. Further reductions may be achieved by the better education of patients about their disease.

Adult↗

Self-monitoring of blood glucose. A survey of long-term use.

A retrospective survey was carried out on all patients within the city of Wollongong who had obtained a home glucose meter in the two-year period from July 1981 to June 1983. From the responses, we found that 49% of patients were not using their meter in an optimal way. Between these patients and those who made optimal use of their meter, the only significant difference was that the former were less likely to have had a machine on loan before purchase. The high percentage of patients making less than optimal use of their home glucose meter indicates a need to review the manner in which these machines are obtained.

Adolescent↗

Can a diagnosis of gestational diabetes be an advantage to the outcome of pregnancy?

OBJECTIVES: We examined the obstetric outcomes of 138 treated women with gestational diabetes mellitus (GDM) compared with 144 women who had a 2-hour, 75-g glucose tolerance test result of between 7.0 and 7.9 mmol/L (126 and 142 mg/dL, respectively). METHODS: The subjects for this study were consecutive patients from a universal testing program for GDM during 1993. Gestational diabetes mellitus was diagnosed if the 2-hour plasma glucose level was 8.0 mmol/L (144 mg/dL) or greater after a 75-g glucose load in the fasting state. RESULTS: Treated women with GDM had a macrosomia rate of 8.0%, which was significantly less (P < .02) than the rate of 17.4% in the "normal" women. Treated women with GDM had a 2.2% rate of fetuses weighing less than 2500 g, which was significantly lower (P = .05) than the 6.9% rate for normal women. Overall, insulin therapy was used in 23.2% of the women with GDM, and no insulin-treated woman had either a macrosomic fetus or a fetus weighing less than 2500 g. CONCLUSIONS: Treated women with GDM, particularly those who receive insulin, have a more favorable fetal outcome than women who have a glucose result between 7.0 and 7.9 mmol/L (126 and 142 mg/dL). These results suggest that the current diagnostic criteria for GDM, with respect to fetal outcomes, may need revision, and an additional subgroup of pregnant women may benefit from dietary advice.

Adult↗

Implementing a holistic approach to diabetes care.

The concept of case assignment is an important development in diabetes education because it encourages a problem-solving approach to care, including evaluation of education, which is the basis of accountability and autonomous professional practice. Furthermore, case assignment and holistic care of clients with diabetes is a model of professional practice that benefits clients, practitioners, and administrators. Case assignment encourages comprehensive and efficient use of human and administrative resources, and provides a foundation for professional development and practitioner autonomy. Effective implementation of holistic care requires a reassessment by health professionals of practice protocols and a reorganization of policy and procedures. The expansion of professional skills necessary for the introduction of a holistic approach will (a) break down traditional practice barriers, and (b) extend the professional knowledge of diabetes care practitioners. Case assignment for diabetes education and follow-up, if extensively adopted, is a mechanism that could contribute to achieving recognition of diabetes educators as independent practitioners, recognition of diabetes education as a practice specialty, and reimbursement for private practitioners.

Diabetes Mellitus↗