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Biomedical subjects

R G Middleton

Publications and source records attributed to R G Middleton.

At least 91 records · Page 5Linked to original sources
PubMed1977

Pelvic lymphadenectomy for the staging of apparently localized prostatic cancer.

Staging pelvic lymphadenectomy has been done on 87 patients with clinically localized prostatic carcinoma. With this method nodal metastases can be discovered, although they are undetectable by any other means. There were 44 patients with negative pelvic lymph nodes by surgical staging subjected to radical prostatectomy. Only 6 patients (14 per cent) had microscopic invasion of the prostatic capsule and there was just 1 instance of microscopic seminal vesicle invasion in those with negative pelvic lymph nodes.

Humans↗
PubMed1977

Block copolyurethanes in the urinary system.

Free floating segments of block copolyurethane were implanted into rat bladders and compared with similar implants of silicone rubber. This urethane was far superior to silicone rubber in its ability to withstand incrustation in the rat bladder. Ten dogs had a segment of right ureter replaced by a tubular segment of smooth (or film) urethane and were followed with intravenous urography. At 1 month, eight of 10 dogs had right hydronephrosis. At the time of sacrifice (4 or 8 months) seven dogs had reduced hydronephrosis, and in three dogs intravenous urography was unsatisfactory for grading. Only two of the ten dogs had significant urinary infection. A smooth protein-like coasting appeared along the lumen of the graft, incrustation was minimal, and new mucosa and smooth muscle regeneration was seen. This material was well tolerated in the urinary tracts of dogs and rats.

Animals↗
PubMed1975

Suprarenal neurilemoma.

Retroperitoneal neurilemomas are rare tumors. They are usually asymptomatic, grow to a large size, and generally undergo cystic degeneration before they are discovered. There may be a palpable flank mass. Almost invariably excretory urography shosw renal or ureteral deviation, and arteriography usually reveals an avascular mass. We present a brief review of the literature and 2 case reports of suprarenal neurilemoma, a site of occurrence not previously reported. One suprarenal neurilemoma occurred in a two-year-old child. The other was removed from a fifty-two-year-old man, and in this case a thoracoabdominal approach was helpful.

Angiography↗
PubMed1975

Staging of localized prostatic carcinoma by pelvic lymphadenectomy: technique using sequential, unilateral extraperitoneal incisions.

A technique for sequential, unilateral, extraperitoneal pelvic lymphadenectomy is described. The procedure is advocated for staging patients with localized prostatic carcinoma in whom all laboratory test results for metastases are negative and in whom definitive radiation therapy or radical prostatectomy is contemplated. This procedure allows complete excision of the regional lymphatic drainage of the prostate with minimal surgical morbidity.

Humans↗