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Biomedical subjects

R G Hansen

Publications and source records attributed to R G Hansen.

At least 37 records · Page 2Linked to original sources
PubMed1981

Pantothenic acid nutritional status in the elderly--institutionalized and noninstitutionalized.

Pantothenic acid nutritional status was evaluated in 37 men (32 noninstitutionalized and five institutionalized) and 54 women (33 noninstitutionalized and 21 institutionalized) 65 yr of age or older. A fasting blood sample, a 24-h urine specimen and a food consumption record for 1 wk were obtained from each subject. Hematological, anthropometric, and dietary parameters indicated these 91 subjects were similar to elderly populations evaluated in other studies. Pantothenic acid was analyzed by both radioimmunoassay and microbiological assay. By combining methods it was possible to differentiate various forms and derivatives of pantothenic acid. Free pantothenic acid, but not the phosphoderivatives, was observed in urine. Microbiological and radioimmunoassay estimations of pantothenic acid showed good correlation (r = 0.91). Pantothenic acid excretion in the institutionalized subjects (7.5 +/- 1.3 (x +/- SEM) mg/g creatinine) was comparable to the excretion levels in the noninstitutionalized subjects (5.9 +/- 0.6 mg/g creatinine). Those consuming pantothenic acid supplements had significantly higher excretion levels. Blood pantothenic acid values between the groups, noninstitutionalized (537 +/- 27.4 ng/ml) and institutionalized (615 +/- 47.3 ng/ml), were comparable. The average dietary intake of pantothenic acid for the elderly population studied was 5.9 +/- 0.1 mg/day with the institutionalized and noninstitutionalized subjects having a similar intake of 2.9 mg/1000 kcal. Institutionalized elderly males and females were consuming 2237 and 1962 kcal, respectively, while their noninstitutionalized counterparts were consuming 2201 and 1887 kcal.

Aged↗
PubMed1981

Pantothenic acid content of a nursing home diet 1,2.

21 meals, representing the usual weekly dietary intake of residents of a northern Utah nursing home, were analyzed for pantothenic acid using a radioimmunoassay. Beverages were not included in the analysis. The mean daily pantothenic acid content of the diet exclusive of beverages was found to be 3.75 mg. The diet as analyzed supplied 2.22 mg of the vitamin per 1,000 kcal. If not supplemented by beverages and snacks, this diet supplies less than the 4-7 mg suggested for adults by the Food and Nutrition Board of the National Academy of Sciences.

Aged↗
PubMed1981

Pantothenic acid content of 75 processed and cooked foods.

Seventy-five foods in a ready-to-eat state were analyzed for pantothenic acid using a new radioimmunoassay. Meats, potatoes, oat cereals, tomato products, and whole grains were among the better sources of pantothenic acid, supplying from 2 to 9 mg. per 1,000 kcal. Fruit products and corn-based and presweetened cereals were among the poorest sources of the vitamin. Results of the study suggest a need for careful selection of foods for pantothenic acid content by individuals on a low-energy diet.

Cooking↗
PubMed1981

Consistency of nutrient consumption patterns in the United States.

With data from the U.S. Department of Agriculture's nutrient densities of diets of 7,810 individuals more than 4 years old were evaluated by use of the Index of Nutritional Quality (INQ) and standard dietary allowances per 1,000 kcal. With the exception of vitamins A and C, the nutritional quality of food consumed by various sex-age groups was remarkably consistent, despite wide variations in total calories consumed. The average concentrations of calcium, iron, magnesium, and vitamin B6 were not sufficient to meet recommended allowances. The reasonableness of recommended standards and the utility of the nutrient density concept for improving food habits of the population are discussed in view of these new data.

Adolescent↗
PubMed1979

Radioimmunoassay for pantothenic acid in blood and other tissues.

We describe a radioimmunoassay for pantothenic acid in biological tissues. D-Pantothenic acid was conjugated with bovine serum albumin by use of a bromoacetyl derivative of pantothenic acid, and antibody to this antigen was raised by injecting it into the foot pads of rabbits. For the radioimmunoassay, a 100-fold dilution of the resulting antiserum was incubated with radiolabeled pantothentic acid. The antibodies were precipitated and dissolved, and the radioactivity of the solution was measured in a liquid scintillation counter. Between 5 and 125 ng of pantothenic acid can be detected in 75 muL of tissue extract. Validation included recovery and precision studies, parallelism with tissue extracts, and competitive binding studies. Results of the radioimmunoassay and those of microbiological assay with use of Lactobacillus plantarum correlated well (r = 0.80).

Aged↗
PubMed1976

An Index of Nutritional Quality for a balanced diet. New help for an old problem.

The Index of Nutritional Quality (INQ) is a method of quantitative and qualitative analysis of single foods, meals, and diets which has special significance in assessing clinical nutritional problems. The INQ is a ratio of the nutrient-to-calorie content of foods which may be calculated by computer and printed as bar graphs and tabular data. The number of nutrients and the nutrient standards used for analysis are flexible parameters which may be varied for each clinical situation. Illustrative examples include INQ analysis of simple foods, an institutional house diet, the diabetic Exchange list, and the diagnostic evaluation of the dietary intake of a hospitalized patient.

Adult↗