Search PubMed⌕ Search

Biomedical subjects

R G Cooper

Publications and source records attributed to R G Cooper.

122 records · Page 7Linked to original sources
PubMed1968

Plesiomonas shigelloides in South Australia.

Plesiomonas shigelloides, a motile, oxidase-positive, Gram-negative rod that may possess shigella antigens, was isolated from the faeces of 36 children and two adults. In 13 children the organism was thought to be possibly the cause of enteritis and in eight children there was no evidence of intestinal disease. In nine children with gastroenteritis other enteropathogenic bacteria were found in addition, and six children had intestinal disease due, or possibly due, to other factors. Only four of the 38 strains had shigella antigens.

Adult↗
PubMed1966

Sex-linked anemia: a hypochromic anemia of mice.

This hereditary anemia is most severe in young mice and tends to diminish with increasing age. Erythrocytes show great variation in size and form, with hypochromia and formation of target cells. Though the anemia occurs on a normal diet, it responds rapidly to iron-dextran injection. It may represent an unusual primary disturbance of iron metabolism.

Anemia, Hypochromic↗
PubMedDate not supplied

DNA variants of alpha-1-antitrypsin in rheumatoid arthritis with and without pulmonary complications.

Restriction fragment length polymorphisms (RFLPs) of alpha-1-antitrypsin were studied in 99 subjects with rheumatoid arthritis alone, 21 subjects with rheumatoid arthritis and pulmonary fibrosis, 26 subjects with rheumatoid arthritis and bronchiectasis, and 86 controls. No associations with either rheumatoid arthritis itself or with the associated pulmonary disorders were noted in this U.K. Caucasoid population.

Alleles↗
PubMedDate not supplied

Measuring outcomes in care of the elderly.

This observational study was designed to assess whether routine measurement of outcomes using standard instruments is possible as part of clinical routine in care of the elderly, and to establish if such instruments are responsive to clinical change. Indices of functional status, cognitive function and subjective health status were collected routinely on admission and discharge in 540 inpatients and 340 patients attending a day hospital. Data collection became integrated into clinical routine. Response rates were generally good and yielded acceptably complete data. For inpatients, outcome was reflected by measurement of survival, physical function (Barthel index) and social status, each of these indicators showing significant change between admission and discharge. For day hospital patients, neither these, nor the Nottingham ADL scale, nor a health status indicator proved sufficiently responsive to clinical change to merit recommendation as outcome indicators for routine use in older patients. In ambulatory care in older patients, such as those attending a day hospital, new approaches are needed to measure clinical outcomes.

Activities of Daily Living↗
PubMedDate not supplied

Load-induced inflexion of the surface electromyographic signal during isometric fatiguing activity of normal human paraspinal muscle.

In twelve normal subjects (aged 21-57 years) changes in surface electromyographic (EMG) activity of the paraspinal muscles were examined during "unloaded" and "weight-loaded" fatigue tests. These comprised 60 second isometric holds against gravity with the upper body unsupported in a horizontal and prone position while the lower body was firmly secured to a couch. During one of the tests sand bags, representing 10% of subjects' body weight, were placed between the scapulae. Integrated EMG (IEMG) and the frequency power spectrum were monitored throughout each test. During both tests IEMG activity initially increased and then plateaued in the unloaded test but decreased in the loaded test. Since frequency changes in the power spectrum were similar during both fatigue tests, IEMG reductions in the loaded test appeared due to reductions in motor unit recruitment. Despite these IEMG reductions the horizontal position was maintained, suggesting the operation of intrinsic peripheral fatigue resistance mechanisms which were utilised to a greater extent during the loaded test.

Adult↗