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Biomedical subjects

R G Auger

Publications and source records attributed to R G Auger.

26 records · Page 2Linked to original sources
PubMed1984

Hereditary form of sustained muscle activity of peripheral nerve origin causing generalized myokymia and muscle stiffness.

Six patients in two unrelated families had a hereditary form of sustained muscle activity of peripheral nerve origin. Although varying in severity among affected family members, the disease was manifested clinically as generalized myokymia and muscle stiffness. Motor and sensory nerve conduction velocities and results of nerve biopsy were normal. Repetitive after-discharges followed each motor nerve stimulus. Needle electrode examination demonstrated spontaneous recurrent bursts of motor unit activity. The burst activity of a motor unit occurred rhythmically (0.5 to 4 bursts per second) and independently of the activity of other units. Within a burst, the firing rate was high (150 to 300 Hz). The clinical and electromyographic abnormalities improved considerably after treatment with carbamazepine or phenytoin.

Adolescent↗
PubMed1981

Microvascular decompression of the facial nerve for hemifacial spasm: clinical and electrophysiologic observations.

Eight patients with idiopathic hemifacial spasm were studied before and after decompression of the facial nerve. Seven patients had an excellent clinical response to surgery, with total resolution of the spasm. One patient had a complete facial palsy and sensorineural deafness on the involved side after surgery, with recurrence of the spasm 6 months later. In all patients, synkinetic activity was present on the involved side before surgery and disappeared after surgery. These findings suggest that the disorder involves the extra-axial portion of the facial nerve. The findings do not require an etiologic role of vascular compression because the response to surgery could be related either to mild trauma of the nerve during the surgical procedure or to subsequent fibrosis.

Adult↗
PubMed1979

Hemifacial spasm: clinical and electrophysiologic observations.

Twenty-three patients with hemifacial spasm were studied clinically and electrodiagnostically. Seven patients had mild facial weakness. All patients had clinical evidence of synkinesis, which often varied considerably. Facial nerve conduction and blink reflex latencies were normal. Facial synkinesis could be measured objectively on the involved side in all patients by simultaneously recording from the orbicularis oculi and orbicularis oris muscles at the time of supraorbital nerve stimulation. Using this procedure, synkinesis was also observed in association with aberrant regeneration after Bell palsy but was not seen in other movement disorders involving the face. The demonstration of synkinesis and its variability in hemifacial spasm can be of value in differentiating hemifacial spasm from other movement disorders affecting the face and provides further insight into its pathogenesis.

Electric Stimulation↗