Search PubMed⌕ Search

Biomedical subjects

R Fujii

Publications and source records attributed to R Fujii.

At least 307 records · Page 17Linked to original sources
PubMed1976

[Characteristics of a mastocytoma cell line adapted to in-vitro culture].

A cell line adapted to in vitro culture was obtained starting from ascites type mastocytoma cells which were maintained by successive transplantation in mice. The cells make colonies in liquid culture medium as well as on agar plate. In comparison under microscope and of behaviour in abdominal cavity of mice, no difference was detected between cells of this cell line and those of original one.

Animals↗
PubMed1975

Transduction of drug resistance to tetracycline, chloramphenicol, macrolides, lincomycin and clindamycin with phages induced from Streptococcus pyogenes.

Strains of Streptococcus pyogenes isolated from pediatric patients with acute infections which were resistant to one or more of the antibiotics, tetracycline (TC), chloramphenicol (CP), macrolide antibiotics (erythromycin, kitasamycin, oleandomycin, josamycin), lincomycin (LCM) and clindamycin (CLM), were used for transduction of drug resistance. These drug-resistant strains were treated with mitomycin C to induce phages and transduction of drug resistance was attempted by means of phages so induced. It was found that transduction of resistance to the above antibiotics was possible. The transductants obtained on TC-containing selective agar plate were resistant to TC alone while those produced on CP- or erythromycin (EM)-containing selective agar plate were resistant to CP, macrolide antibiotics (Mac), LCM and CLM. From this finding, it was inferred that transduction of resistance to TC, CP, Mac, LCM and CLM via phages occurred in two different patterns, i.e., transfer of resistance to TC alone and that of resistance to CP, Mac, LCM and CLM. All of the transductants obtained were found to belong to group A. In T-typing, they were of the same T-12 type as the donor and recipient strains in a majority of cases though some were not typable.

Anti-Bacterial Agents↗