[Rupture of the fornix. A contraindication of intravenous urography?].
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Extravasation of Diagnostic and Therapeutic Materi↗
Biomedical subjects
R Friedrichs
Publications and source records attributed to R Friedrichs.
Differential diagnosis and therapy of rare testicular tumors.
The origin, differential diagnosis and therapy of rare testicular tumors are reviewed. 5% of all testicular tumors are rare tumors. Most of these rare tumors are of non-germ cell origin.
Diagnosis, Differential↗
[Evaluation of spontaneous renal extravasation of contrast media in the excretory urogram].
Spontaneous renal extravasation is the term used to refer to the radiological demonstration of contrast medium outside the collecting system without previous trauma, ureter catheterization, operation on the kidney or its vicinity, and without external compression during urography. In a review of 1300 intravenous urograms, 13 cases of extravasation of contrast medium were found to satisfy the above criteria. Differences in the radiological appearance may cause problems with regard to evaluation and classification. From a therapeutic point of view it is important to distinguish between two forms: transient sinus extravasation due to minute tears in the calyceal fornix after an increase in intrapelvic pressure and persisting rupture of the previously impaired renal pelvis, which may require surgical intervention.
Adult↗
Glycosaminoglycans in urothelial carcinomas.
The glycosaminoglycan (GAG) content in human urothelial carcinomas was biochemically determined and compared to that of normal urothelium and bladder wall of the calf. The total GAG content was elevated in urothelial carcinomas, and the distribution pattern differed from that of normal urothelium and bladder wall. Whereas urothelial carcinomas contained heparan sulphate, dermatan sulphate, chondroitin 4-sulphate and chondroitin 6-sulphate, only heparan sulphate could be detected in the normal urothelium. The GAG determination was based on hexosamine analysis and thin layer chromatography after elution on Dowex 1 X 2 columns.
Aged↗
Quantitative analysis of glycosaminoglycans in urothelium and bladder wall of calf.
Glycosaminoglycans (GAG) were described by histochemical staining procedures in the normal urothelium of the urinary bladder; they are supposed to be involved in the antibacterial defense mechanism. Our quantitative analysis, however, demonstrated only heparan sulfate in the normal calf urothelium (less than 600 nmol/Gm d.wt.); only trace amounts of other GAG were to be analyzed. High concentrations of GAG were found in the submucosa and muscle layers as to be expected in mesoderm originating tissues. According to these results there were no GAG with the exception of heparan sulfate at the surface of the normal urothelium; therefore, glycoproteins detected in mumol/Gm d.wt. ranges are more likely to be involved in the antibacterial defense mechanism.
Animals↗
Intravesical single and combination therapy in superficial bladder cancer. An experimental study.
In this animal experiment it was investigated if intravesical combination therapy is superior to single drug therapy to reduce the growth of N-butyl-N(4-hydroxybutyl)-nitrosamine (BBN)-induced bladder carcinomas in the rat. The evaluation of the histological data gave the following results: intravesical instillation of cytostatic drugs in concentrations similar to that used in man reduce the growth of BBN-induced tumors. The effectiveness of mitomycin C or adriamycin alone is similar to that of alternative administration of mitomycin C and adriamycin.
Animals↗
Effect on hearing thresholds of surgical modification of the external ear.
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Auditory Threshold↗