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Biomedical subjects

R Frey

Publications and source records attributed to R Frey.

At least 181 records · Page 10Linked to original sources
PubMed1976

[Intensive care in ENT medicine, head and neck surgery (author's transl)].

In intensive medicine we distinguish between intensive care units which have mostly observatory and monitoring functions and intensive therapy units. For the surgical patients of the ear, nose, and throat department the intensive care units are probably of greater significance. The following play an important role: Preoperative work-up including laboratory fluoroscopy and x-rays, pulmonary function tests and blood gas analysis; induction of anesthesia, access to good veins, gastric intubation, urinary bladder catheterization; maintenance of anesthesia and postoperative observation, fluid balance, oral and parenteral feeding, tracheostomy care, bronchial toilet; inhalation therapy. The last receives an extensive discussion.

Acid-Base Equilibrium↗
PubMed1975

Changes in DNA secondary structure after gamma-irradiation.

Native calf thymus DNA was gamma-irradiated at 500 mug/ml in 0.01 M NaCl in the presence or absence of oxygen. By irradiation, an increasing amount of DNA becomes reactive with a water-soluble carbodiimide-derivative (CMEC). In the DNA sections reactive with CMEC the nucleotide strands are separated, a phenomenon previously described as radiation-induced denaturation. The dose-effect curve for the formation of denatured DNA shows an upward-bent form; a distinct oxygen effect of about 2 is observed. By a comparative study with DNA samples, degraded partially with DNAse I, it was shown that a minor part of the radiation-induced denaturation results from the formation of the radiation-induced single strand breaks, whereas the major part is a local denaturation independent of the strand breaks. In these locally denatured regions 20 to 50 nucleotide pairs are separated.

Animals↗