Mathematical model of dose-activity relationships.
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Dose-Response Relationship, Drug↗
Biomedical subjects
R Franke
Publications and source records attributed to R Franke.
Quantitative structure-activity relationships in phytotoxic piperidinoacetanilides.
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Acetanilides↗
[Modelling of enzyme-active substance interactions].
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Drug Interactions↗
[Antiviral thiosemicarbazone and related compounds. III. Quantitative relationships between structure and antiviral activity of isantin-beta-isothio-semicarbazone against mengo virus].
The virostatic activity of isatin-beta-isothiosemicarbazones can be described quantitatively by hydrophobic, electronic, and steric substituent constants using multivariate regression analysis. A preceding Free-Wilson analysis allows data smoothening, and thus improved adaptation. Predictions made on the basis of the quantitative structure-action relationships obtained could be confirmed experimentally by synthesizing and testing the corresponding compounds.
Antiviral Agents↗
Quantitative structure-activity relationships in immunosuppressive nitrogen mustard benzimidazoles.
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Animals↗
[Quantitative structure-activity relationships for biologically active sydnones].
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Aminopyrine N-Demethylase↗
Structure-activity relationships in polycyclic aromatic hydrocarbons: induction of microsomal aryl hydrocarbon hydroxylase and its possible importance in chemical carcinogenesis.
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Adrenal Glands↗
[Quantitative structure-activity relationships for the induction of microsomal azo-dye N-demethylase by polycyclic aromatic hydrocarbons].
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Animals↗
[Current problems in drug research. I. Determination of the quantitative structure-activity relationships of biosubstances: theoretical principles, accomplishments, assumptions and present state].
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Biological Transport↗
[Quantitative structure-activity relationships in virostatically active isatin-beta-thiosemicarbazones].
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Absorption↗
[Parabolic relationship between biological activity and hydrophobicity in congenergic series: transport or protein binding?].
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Animals↗
[Polymorphism of various serum proteins in cattle].
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Alleles↗
[Determination of protein binding constants of extremely sparingly soluble compounds].
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Benzopyrenes↗
[Penetration electrode for continuous pO 2 measurement in tissue].
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Adult↗
[Capillary blood collection in the newborn].
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Acid-Base Equilibrium↗
[Oxygen partial pressure measurements in the fetus during labor].
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Amplifiers, Electronic↗
[Relationship between electronic transition energies, carcinogenic activity and hydrophobic binding of protein to polycyclic aromatic hydrocarbons].
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Carbohydrates↗
[Granulosa cell carcinoma in pregnancy and cytostatic therapy in early post-partum period].
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Adult↗