Induction of invertant males in E. coli K12.
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Biomedical subjects
Publications and source records attributed to R Fournier.
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Compression therapy is frequently used to prevent hypertrophy of post-burn scars. This pilot study was performed in 6 patients to assess non-invasive changes induced in the tensile strength of the skin before any clinical improvement can be perceived. Assessments were performed using a computerized suction device delivering three 5 s cycles of 500 mbar depression. Measurements were made at one-month intervals for three months after initiating the garment compression therapy. Comparisons were made between the intact skin, the ungrafted and grafted post-burn scars and the graft donor sites. Data show that garment compression therapy alters the tensile strength in the skin of all test sites. The most reliable variations consist of an increase in both the extensibility and elasticity of the tissues submitted to traction.
The following main points emerge from this analysis: -- Whilst all cases of hydronephrosis do not require operation, in the long term future of a non-operated hydronephrosis is difficult to predict and the risk of avoiding surgery is not definitely less than that of operation. -- Adult hydronephroses are much more often complicated by lithiasis (16 cases in 82 hydronephrotic kidneys) than those seen in children (4 cases in 36 hydronephrotic kidneys). -- The prognosis if hydronephrosis, especially with lithiasis, affecting a horseshoe kidney is particularly poor, without there being any clear explanation for this fact. -- Anderson-Hynes plasty of the pelvi-ureteric junction would seem to be a reliable operation, even more in the child than the adult. However, even when carried out perfectly, it provides no gaurantee against the development or secondary development of lithiasis, even when dilatation and urinary stasis have disappeared. Thus very prolonged surveillance is necessary after such surgery, above all when the hydronephrosis was accompanied by lithiasis.
Five cases were related to gynaecological surgery and 4 to operations involving the colon and rectum. In digestive surgery, the ureteric lesion was noted and repaired in 3 cases out of 4. By contrast, in gynaecology, it went unnoticed in all cases and was diagnosed and repaired after an interval varying from 6 weeks to 4 years after the trauma. 4 anti-reflux uretero-vesical reimplantations and one uretero-ureteric anastomosis were carried out, with complete success in all 5 cases. It is particularly striking to note that in gynaecological surgery 4 of the 5 ureteric lesions followed surgery for a non-malignant condition and that the ureteric trauma should have been easy to avoid, in particular by the preoperative insertion of ureteric catheters. By contrast, all the cases in digestive surgery were associated with operations for a carcinoma. In 3 cases out of 4, excision of the tumour necessitated the sacrifice of a segment of the ureter in the pelvis. One end-to-end ureteric suture failed, whilst 2 uretero-ureteric anastomoses were both successful.
The authors' experience involves 11 cases. In four instances, insertion of the ureteral catheter via endoscopy was impossible. Two of these patients were not subjected to surgery because of their great age. In the other two, anti-reflux uretero-vesical reimplantation and insertion of a modelling ureteral catheter was carried out by an open surgical approach. A good result was obtained in both. In the other six patients, it was possible to insert the catheter via endoscopy. This gave five successess and one failure. The single failure was a case of long standing tuberculous stenosis of the ureter. The modelling ureteral catheter, when inserted by endoscopy, gives, in combination with corticosteroids and anti-tuberculous therapy, almost constantly successful results in recent cases of stenotic tuberculosis of the ureter in young patients.