A positive surface potential indicating a cell coating is common to malignant cells, lymphocytes, and normal and malignant trophoblastic cells. This characteristic was not generally found for other normal cell types tested by microelectrode penetration.

Animals↗

PubMed1970

A malignant trophoblastic cell line: high rates of DNA synthesis measured by a rapid disc method.

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Animals↗

PubMed1969

Steroidogenesis of the menopausal and postmenopausal ovary.

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17-Ketosteroids↗

PubMed1969

Progesterone synthesis in the pure trophoblasts of human choriocarcinoma.

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Cell Line↗

PubMed1969

Carbohydrate metabolism of choriocarcinoma in continuous tissue culture.

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Carbohydrate Metabolism↗

PubMed1969

Ultrastructure and hormone synthesis of choriocarcinoma in vitro.

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Cell Differentiation↗

PubMed1968

Human hormone production in vitro.

A new in vitro hormone-synthesizing cell system, line BeWO, derived from human gestational choriocarcinoma, has been permanently established; a high degree of synthesis of functional hormone has been maintained for 18 months in tissue culture. Predominantly glycolytic metabolism, dependent on the level of glucose in the medium, has been observed. Many facets of placental and tumor-cell metabolism, growth, and differentiation are found in this unique multipotential cell.

Biological Assay↗

PubMed1968