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Biomedical subjects

R F Harvey

Publications and source records attributed to R F Harvey.

At least 73 records · Page 4Linked to original sources
PubMed1981

Functional performance assessment: a program approach.

An interdisciplinary method of functional assessment is presented utilizing the Patient Evaluation Conference System, or PECS (Harvey and Jellinek, 1979), which has been successfully applied to a medical rehabilitation setting to guide treatment and to assess program effectiveness. Our method requires that functional performance items be evaluated in terms of progress using an 8-point, 0 to 7 scale, 0 representing unmeasured or unmeasurable function, and 7 representing fully independent or normal function. Rehabilitation outcomes of 4 or below present varying degrees of dependent function, and outcomes of 5 or more represent degrees of independent function. Data are presented which demonstrate level of gain, goal-setting effectiveness, and degree of independent function.

Computers↗
PubMed1979

Colonic motility in proctalgia fugax.

Intraluminal pressure recordings were obtained from the rectum and sigmoid colon in two patients experiencing attacks of proctalgia fugax. In each patient the pain appeared to result from contractions of the sigmoid colon, and not from spasm of the levator ani, rectal wall muscle, or anal sphincters, all of which have previously been suggested as the source of such pain. Proctalgia fugax therefore appears, at least in some patients, to be an unusual variant of the irritable bowel syndrome, in which pain is referred from the sigmoid colon to the rectum.

Adult↗
PubMed1979

Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.

Levels of immunoreactive trypsin were measured in pure pancreatic juice obtained endoscopically from 44 patients with suspected pancreatic disease. Patients with pancreatic cancer all had low trypsin concentrations (median 3.6 micrograms/ml, range 0.6--12.0), but those with chronic pancreatitis had very variable levels (median 14.2 micrograms/ml, range 3.2--76.8), showing a considerable overlap with patients without pancreatic disease (median 37.1 micrograms/ml, range 10.4--66.0). When levels of lactoferrin in pancreatic juice were measured, all patients with chronic pancreatitis were found to have much higher levels (all greater than 900 ng/ml) than control subjects or patients with pancreatic cancer (all less than 400 ng/ml). The combined measurement of trypsin and lactoferrin in pure pancreatic juice appeared to be more promising than any other currently available test for the separation of patients with pancreatic cancer from those with chronic pancreatitis.

Chronic Disease↗
PubMed1978

Gut-hormone profile.

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Gastrointestinal Diseases↗
PubMed1978

Radioimmunoassay of lactoferrin in pancreatic juice as a test for pancreatic diseases.

Lactoferrin, a protein present in pancreatic juice and other exocrine secretions, was measured by radioimmunoassay in pure pancreatic juice obtained by endoscopic cannulation of the pancreatic duct. Lactoferrin concentrations were high in pancreatic juice from patients with chronic pancreatitis, but they were considerably lower in juice from control subjects and patients with carcinoma of the pancreas. The measurement of lactoferrin concentrations in pure pancreatic juice may be useful in the diagnosis of pancreatic diseases.

Chronic Disease↗
PubMed1978

Preparation of prereduced anaerobically sterilized media and their use in cultivation of anaerobic bacteria.

Several modifications of the roll-tube method have made it simpler for routine use in the isolation and growth of anaerobic bacteria. These include use of a check valve for the production of prereduced anaerobically sterilized media; a Salvarsan tube under oxygen-free gas pressure for the dispensing of molten prereduced anaerobically sterilized agar medium; a Kelly infusion bottle with a graduated pipette side arm (also under gas pressure) for quantitative delivery of fluid prereduced anaerobically sterilized media; and screw-capped prescription bottles for the cultivation of anaerobes. Colonies of Bacteroides melaninogenicus were easily identified and counted by this method. Other anaerobic bacteria have also been cultivated successfully.

Anaerobiosis↗
PubMed1977

Wheat fibre and irritable bowel syndrome. A controlled trial.

Twenty-six patients with irritable bowel syndrome entered a controlled trial of diets with a high or low wheat-fibre content. After 6 weeks on the high-wheat fibre regimen there was significant improvement in symptoms and an objective change in colonic motor activity. No such improvement occurred on the low-fibre regimen. Patients with irritable bowel syndrome should be encouraged to increase their daily intake of wheat fibre.

Adult↗
PubMed1977

Inhibition of cholecystokinin-pancreozymin release by somatostatin.

To determine the effect of somatostatin on cholecystokinin-pancreozymin (C.C.K.) release, serum-C.C.K. concentrations were measured in normal volunteers after intraduodenal olive oil, with and without a simultaneous intravenous infusion of somatostatin. After instillation of the olive oil there was a rapid rise in serum-C.C.K. (integrated response 19 682+/-5632 pg min ml-1). This rise was completely abolished by somatostatin (integrated response -373+/-330 pg min ml-1, P less than 0-005) and rebound hyper-secretion was seen after the infusion had been stopped. These findings indicate that somatostatin may be involved in regulating C.C.K. release after meals, and suggest a possible explanation for the profound steatorrhoea seen in a patient with a somatostatin-producing tumour.

Adult↗