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Biomedical subjects

R F Gray

Publications and source records attributed to R F Gray.

52 records · Page 3Linked to original sources
PubMed1982

Swimming after laryngectomy.

The philosophy and practicalities of a device for safe swimming after total laryngectomy are considered. The design and use of this are described in a patient who enjoys a great success swimming both in and underwater. Rehabilitation of the laryngectomee may include swimming, if desired, where training and supervision are available. Safety precautions are recommended.

Adult↗
PubMed1981

Round window rupture.

Eight patients suffered sudden sensory neural hearing losses associated with exertion or trauma; all were found at tympanotomy to have round window membrane ruptures with leakage of perilymph. Operative findings, with audiometric, radiological and electrocohleographic results are shown. The aetiology is discussed, with particular reference to diving techniques and to the cochlear aqueduct.

Adult↗
PubMed1980

Primary atrophic rhinitis: a scanning electron microscopic (SEM) study.

The surface features of atrophic rhinitis are shown and it is suggested that these explain the majority of symptoms. It seems clear that any lesion preventing the formation or maturation of large numbers of motile cilia, or the production of mucus capable of forming confluent sheets suitable for continuous propulsion, may cause atrophic rhinitis. In both familial and idiopathic forms of the disease, both abnormalities are present. It would be most interesting to know the ultrastructure of the cilia in transverse section of this condition. Transverse electron microscopic studies in Retinitis Pigmentosa, Usher's syndrome and Kartagener's syndrome now becoming known as the low cilia motility diseases show clearly the primary lesions in the micro-tubules and dynein arms of the cilia. A similar transmission electron microscopic study in atrophic rhinitis may show the fundamental cilial lesions. Surgical closure of the nasal passages has much to offer the patient with severe symptoms as the clinical features of the disease improve with the increasing normal micro-anatomical features demonstrated in this paper as a result of closure. This improvement in structure is not in all cases sufficient to fulfil the above criteria so a complete cure is improbable in the majority of cases.

Adolescent↗
PubMed1979

The clinical evaluation of a new clobetasol propionate preparation in the treatment of otitis externa.

A new preparation containing clobetasol propionate, tetracycline and nystatin was compared with Otosporin in the the treatment of otitis externa. Thirty-two patients with bilateral disease and seventeen with unilateral disease completed the trial. Signs and symptoms were assessed by the clinician initially and at varying times after treatment. Both preparations were effective in relieving the symptoms with the majority of patients noticing improvement within seven days. Clobetasol propionate ear drops were significantly better than Otosporin when assessed on the patient's last visit to the hospital (p less than 0.05). There were less relapses in the clobetasol propionate group than in the Otosporin group.

Adolescent↗
PubMedDate not supplied

Response of the endolymphatic sac in the guinea pig to neomycin ototoxicity.

The guinea pig provides an excellent model for studying the effects of ototoxic antibiotics on the epithelium of the endolymphatic sac (ELS). Intracochlear injection of neomycin produces consistent destruction of cochlear and vestibular sensory cells, and the response to this traumatic insult can be documented by light and electron microscopy of the ELS. The histologic findings suggest that ELS epithelial cells are relatively resistant to ototoxic levels of neomycin. The study confirms the ability of the ELS to increase its activity during periods of labyrinthine stress.

Aminoglycosides↗