Search PubMed⌕ Search

Biomedical subjects

R F Bornstein

Publications and source records attributed to R F Bornstein.

42 records · Page 3Linked to original sources
PubMed1986

Parental representations and orality.

One hundred ninety-three undergraduate male subjects were administered a Rorschach orality measure (Masling, Rabie, & Blondheim, 1967), and completed copies of Blatt, Wein, Chevron, and Quinlan's (1981) Parental Representations measure. A significant correlation between orality and quality of parental representations was found, with high oral subjects giving more negative descriptions of the mother than low orals. No relationship between orality and the conceptual level of parental descriptions was found. The implications of these findings are discussed in the context of psychodynamic formulations regarding the oral personality.

Journal Article↗
PubMed1986

Discriminant validity of the General Behavior Inventory: an outpatient study.

Recent studies have provided strong support for the convergent validity of the General Behavior Inventory (GBI), a case identification inventory for chronic subsyndromal affective disorders (cyclothymia and dysthymia). Fewer data are available, however, on the ability of the GBI to distinguish chronic subsyndromal affective disorders from other forms of psychopathology. In order to address this issue, outpatients with cyclothymia (n = 9), dysthymia (n = 26), nonchronic major depression (n = 16), and nonaffective psychiatric disorders (n = 30) were compared on the GBI. Diagnoses were derived blind to GBI scores using structured diagnostic interviews and DSM-III criteria. The inventory significantly discriminated cyclothymes and dysthymes from patients with nonchronic major depressions and nonaffective disorders. Using the cutoff score that maximized GBI-diagnosis concordance, the inventory correctly classified 88% of the sample. All of the cyclothymes, 92% of the dysthymes, 87% of the patients with nonaffective psychiatric disorders, and 75% of the nonchronic major depressives were correctly classified by the inventory. These data provide strong support for the discriminant validity of the GBI.

Adult↗
PubMed1985

Orality and latency of volunteering to serve as experimental subjects: a replication.

Comparison of Rorschach orality scores for undergraduate subjects who signed up to participate in psychology experiments during the first (n = 217) and second (n = 87) halves of the semester revealed that early participators report a significantly (p = .03) greater number of oral Rorschach responses (X = 3.765) than late participators (X = 3.218). This result confirms an earlier serendipitous finding (Masling, O'Neill, & Jayne, 1981) that volunteering to participate in required experiments is not a chance event and can, in fact, be predicted using methods derived from psychoanalytic theory. Our finding supports the utility of psychoanalytic principles in predicting important aspects of nonlaboratory behavior.

Journal Article↗
PubMed1982

A sodium requirement for growth, solute transport, and pH homeostasis in Bacillus firmus RAB.

Activity of a Na+/H+ antiporter has been suggested to be critically involved in pH homeostasis in obligately alkalophilic bacteria (Krulwich, K. A., Mandel, K. G., Bornstein, R. F., and Guffanti, A. A. (1979) Biochem. Biophys. Res. Commun. 91, 58-62) and in Escherichia coli (Zilberstein, D., Padan, E., and Schuldiner, S. (1980) FEBS Lett. 116, 177-180). A concern with respect to these proposals has been the failure of either Bacillus alcalophilus or E. coli to exhibit a requirement for added Na+ for growth. Thus, it became of interest to examine Na+-coupled porter functions in obligately alkalophilic Bacillus firmus RAB, a species that exhibits an absolute requirement for added Na+ for growth at pH 10.5. In a comparative study using membrane vesicles from B. alcalophilus and B. firmus RAB it was found that both the Na+/H+ antiporter and the Na+/alpha-aminoisobutyric acid symporter from the "Na+-requiring" species had much lower apparent affinities for Na+ than corresponding porters from B. alcalophilus. At high concentrations of Na+, the porters from the two species were functionally similar. These findings support the argument that the absence of a growth requirement for added Na+ may reflect an ability of at least some bacteria to effectively utilize and recycle the available levels of Na+ that contaminate all media, rather than reflect true Na+ independence. Studies with a nonalkalophilic derivative of B. firmus RAB confirmed earlier findings with B. alcalophilus of a pleiotropic loss of Na+ coupling to porters in nonalkalophilic mutants.

Aminoisobutyric Acids↗
PubMed1981

Oxidative phosphorylation by membrane vesicles from Bacillus alcalophilus.

ADP and Pi-loaded membrane vesicles from t-malate-grown Bacillus alcalophilus synthesized ATP upon energization with ascorbate/N,N,N',N'-tetra-methyl-P-phenylenediamine. ATP synthesis occurred over a range of external pH from 6.0 to 11.0, under conditions in which the total protonmotive force delta-mu-H+ was as low as -30 mV. The phosphate potentials (delta Gp) were calculated to be 11 and 12 kcal/mol at pH 10.5 and 9.0, respectively, whereas the delta-mu-H+ values in vesicles at these two pH values were quite different (-40 +/- 20 mV at pH 10.5 and -125 +/- 20 mV at pH 9.0). ATP synthesis was inhibited by KCN, gramicidin, and by N,N1-dicyclohexylcarbodiimide. Inward translocation of protons, concomitant with ATP synthesis, was demonstrated using direct pH monitoring and fluorescence methods. No dependence upon the presence of Na+ or K+ was found. Thus, ATP synthesis in B. alcalophilus appears to involve a proton-translocating ATPase which functions at low delta-mu-H+.

Bacillus↗