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Biomedical subjects

R Esposito

Publications and source records attributed to R Esposito.

At least 127 records · Page 7Linked to original sources
PubMed1979

[Activity of coagulation factors in liver coma caused by viral hepatitis].

Coagulation studies were performed on 8 patients with acute liver failure from viral hepatitis. Four died and four recovered. At the time of development of coma, levels of clotting factors resulted markedly reduced in all cases and were not of value as a prognostic index. Subsequent serial determinations (every 8 hours) during the evolution of coma showed that prothrombin activity and levels of factor I, II, V and X were not correlated with clinical conditions, most probably owing to the influence of the administration of blood and blood components. Of all coagulation tests, the assay of factor VII, which has the shortest half-life, appeared the most reliable index of hepatic synthetic function at a particular point in time.

Adolescent↗
PubMed1977

[Histochemical detection of HBsAg in liver biopsies using the orcein staining method].

Liver biopsies from 30 HBsAg seronegative and 33 HBsAg positive subjects affected by liver diseases were stained by orcein method for the histochemical detection of HBsAg. All biopsies from HBsAg negative cases were orcein negative. Staining was positive in 55% of seropositive patients. The frequency of the different patterns of the staining is analyzed and its value as a diagnostic and prognostic tool in chronic liver disease is discussed.

Antibody Formation↗
PubMed1976

Serum alpha-fetoprotein in viral hepatitis and its complications.

Alpha-fetoprotein levels were measured by radioimmunoassay in 40 cases of acute viral hepatitis, 5 cases of chronic persistent hepatitis, 15 cases of chronic aggressive hepatitis and 5 cases of hepatic coma from fulminant viral hepatitis. Serum concentrations were increased in 55% of patients with acute viral hepatitis and in about 33% of patients with chronic aggressive hepatitis. Levels resulted markedly raised among the patients with coma from fulminant viral hepatitis who survived. The high aplha-fetoprotein values may reflect liver cell regeneration after necrosis of a critical mass of hepatic tissue.

Acute Disease↗
PubMed1975

[Use of a new oral antibiotic in surgery].

Results with pivampicillin, a new ampicillin with complete gastric absorption and capable of producing high tissue levels, in the prevention and treatment of postoperative infection in 31 cases are presented. The antibiotic was effective in 29 cases, 4 of which had a prior history of antibiotic intractability. Side-effects consisted of slight gastric disturbances, with suspension of treatment in 1 case only. No clinically significant changes in the laboratory data were noted.

Adult↗
PubMed1975

Anabolic agents in kidney disease: the effect of formebolone on protein synthesis in patients with renal insufficiency or nephrosis.

The anabolic activity of formebolone was studied in 7 patients with nephrosis or renal insufficiency by measuring the amount of 14C-leucine incorporated into plasma proteins as an index of protein synthesis. The data demonstrate that the incorporation of label into the plasma albumin fraction was significantly increased after formebolone administration.

Acute Kidney Injury↗
PubMed1975

Urea index and nitrogen balance in uremic patients on miminal nitrogen intakes.

Normal anduremic subjects were studied on different protein intakes. The uremic patients were also given minimal amounts of nitrogen in the form of 8 essential amino acids, with or without the addition of histidine. It was noticed that as little as 416 mg of essential amino acid nitrogen was sufficient to cover body needs if enough non-essential nitrogen was present. It was also demonstrated that on low-nitrogen intakes, the ratio of urinary urea to total urinary nitrogen varied with nitrogen balance.

Adolescent↗
PubMed1975

[Radioimmunologic determination of the Australia antigen during the course of viral hepatitis].

Australia Antigen was detected by radioimmunoassay technique in 80 cases of viral hepatitis. Incidence of the antigen was 40% in patients with epidemiologic data of infectious hepatitis, 84% in patients with epidemiologic data of serum hepatitis and 61% in a group of patients not reporting a reliable epidemiologic history. The count rate was periodically determined during the course of the illness in the attempt to evaluate, within the limits of the method, the amount of the antigen in the serum samples. Results are briefly discussed, together with the problem of the correlation between the presence of Australia Antigen and the two types of hepatitis infection.

Antibodies, Viral↗