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Biomedical subjects

R E Stowell

Publications and source records attributed to R E Stowell.

At least 19 recordsLinked to original sources

Pathology in the Soviet Union.

Five pathologists from the United States visited the Soviet Union for three weeks in April 1978 to learn of the training in and the practice of pathology in that country. The major observations of the Americans were that (1) pathology is a medical specialty in the Soviet Union, with practice limited to anatomic pathology; (2) exfoliative cytology and clinical pathology are not part of pathology; (3) interest, both clinical and experimental, in occupational, environmental, and geographic pathology is conspicuous; (4) an autopsy rate of 90% to 95% is customary; and (5) there is an organized and hierarchical framework for practice, with career patterns established early and change infrequent.

Autopsy

Laser microscope irradiation of Physarum polycephalum: dynamic and ultrastructural effects.

Streaming plasmodia of Physarum polycephalum were irradiated with a microscope-mounted ruby laser and the resulting changes were recorded by cinemicrography or streak photographs. Some lesions were processed for electron microscopy. By varying the incident energy, three levels of response were detected. Two transient responses, a gelation briefly blocking streams and a more severe gelation with contraction, changed movement patterns but not organelle ultrastructure. At higher energies, a permanently coagulated lesion was rapidly segregated from normal and transiently altered cytoplasm by formation of new membranes. Within the coagulum, pigment granules were destroyed, membranes were disrupted, and cytoplasm was flocculent. Nuclei and mitochondria were compact in the center and swollen in a peripheral space left by contraction of the coagulum. These changes are probably caused by heat produced by the interaction between the laser beam and the pigment granules of the plasmodium. Many of the changes seem to be secondary responses that follow the primary capture of energy during irradiation.

Cell Nucleus