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Biomedical subjects

R E Kunz

Publications and source records attributed to R E Kunz.

5 recordsLinked to original sources
PubMed2001

Compact integrated optical sensor system.

A compact integrated optical sensor system for a large variety of different (bio-) chemical applications using replicated sensor chips is described. Features of the refractometric system to be emphasized for practical applications include a high-resolution window that can be positioned within a wide measuring range, an in situ chip testing and characterization procedure, and on-chip referencing. As an application example, experimental results on refractometric measurements as well as on the suppression of non-specific binding are given.

Biosensing Techniques↗
PubMed2000

Single-pad scheme for integrated optical fluorescence sensing.

A new scheme for integrated optical fluorescence sensing is presented. The principle is based on a planar waveguide containing multiple sensing units, each consisting of a single-pad grating coupler structure. Single-pad means that all the following functions are incorporated in one single pad: laser light input, excitation of the labeled analyte molecules, efficient collection of the emitted fluorescent light into the waveguide, background suppression, and coupling the guided wave out to the detector. The results demonstrate a high efficiency of the fluorescence light excitation and collection, as well as a good suppression of the volume background.

Biosensing Techniques↗
PubMed1998

Novel integrated optical sensor based on a grating coupler triplet.

A novel approach for accomplishing robust integrated optical biosensors is presented. The principle is based on a symmetric grating coupler structure with the inherent feature of compensating disturbances originating from different kinds of mechanical instabilities. The complete sensor system has no moving parts and provides the high sensitivities typical for integrated optical sensors based on grating couplers. The feasibility of this approach is demonstrated by determining the refractive index of liquids as well as by measuring the specific binding of biomolecules (anti-chicken IgG) to immobilized chicken IgG on the sensor chip surface.

Biosensing Techniques↗
PubMed1993

Transverse plantar incision for heel spur surgery. Four-year follow-up survey of 35 patients.

A transverse plantar incisional approach was used on 35 patients who underwent heel spur surgery from 1982 through 1990. Ten bilateral procedures were performed on a total of 45 feet. A medial approach was used for five of the bilateral surgeries. The average age of the patient was 47 years, and the average follow-up period was 49 months. Of the 34 plantar approach cases in which complete data were obtained, 94% showed either good or excellent results. The authors illustrate a technique using a transverse plantar incision as an alternative to the medial approach for heel spur surgery.

Calcaneus↗