Biomedical subjects

R E Hayden

Publications and source records attributed to R E Hayden.

58 records · Page 4Linked to original sources

PubMedDate not supplied

Hemangiomas of the sphenoid sinus.

A review of the literature reveals that primary tumors of the sphenoid sinus are rare. No vascular tumors of the sphenoid have been previously reported. Two patients with cavernous hemangiomas of the sphenoid sinus are presented, both of whom died of complications associated with the diagnostic biopsy. A review of the available routine and special diagnostic tests is presented. The importance of an awareness of vascular tumors in this region is stressed.

Adult↗

PubMedDate not supplied

Revascularized iliac bone graft for mandibular reconstruction.

Revascularized iliac bone has advantages over other revascularized bone grafts for the reconstruction of large mandibular defects. This is a detailed anatomical study of the blood supply to the iliac bone using microfil and Batson injection methods. It confirms and extends Taylor's study. Clinical results are reported for six cases of extensive mandibular defects which were reconstructed using this method.

Aged↗

PubMedDate not supplied

Merkel cell tumor-like neuroendocrine carcinoma associated with the submandibular gland. Report of a case with cytologic, immunohistochemical, electron microscopic and flow cytometric studies.

We report a rare case of primary Merkel cell tumor (MCT)-like neuroendocrine carcinoma (i.e., small cell carcinoma) associated with the submandibular gland in a 73-year-old man. Despite the lack of a known skin primary, the tumor exhibited cytomorphologic (predominant single cells with "intermediate filament buttons" in the background), ultrastructural (dense core granules and a globular aggregate of intermediate filaments) and immunohistochemical (paranuclear globular coexpression of cytokeratin and neurofilaments) features identical to that of MCT. The tumor contained an aneuploid peak with DNA index of 1.1 and an S phase of 20.5%. The tumor measured 5.8 cm and was situated between the skin and submandibular gland, with which it was closely associated but separated by connective tissue. The literature on MCT without a known skin primary is reviewed, and the cytomorphologic features that allow the distinction between MCT, lymphoma and oat cell carcinoma are discussed.

Aged↗

PubMedDate not supplied

Olfactory neuroblastoma: MR evaluation.

PURPOSE: To evaluate MR in the diagnosis and staging of olfactory neuroblastoma. METHODS: Five patients with histologically proved olfactory neuroblastomas were studied by MR. Four also had CT scans. RESULTS: The extent of disease delineated by MR agreed with surgical findings and surgical staging of the tumor in all five patients. All cases of olfactory neuroblastomas originated in the nasal cavity and involved the ethmoid sinuses. In three of the five cases, the tumors extended to the anterior skull base. In one case MR correctly suggested skull base involvement missed on CT. Lesions were isointense to hyperintense with muscle on T1-weighted scans. Compared with fat on T2-weighted scans, olfactory neuroblastomas were variable in signal intensity. Enhancement was minimal to moderate in all cases. CONCLUSION: In the evaluation of olfactory neuroblastoma, MR is most useful in delineating the extent of the tumor and may be more accurate than CT. However, the signal intensity characteristics of olfactory neuroblastomas may overlap other tumors.

Adolescent↗