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Biomedical subjects

R E Hall

Publications and source records attributed to R E Hall.

113 records · Page 7Linked to original sources

Advances in maxillofacial imaging.

The maxillofacial region, extending from the base of the skull to the hyoid bone, is one of the most anatomically complex regions of the body. This area contains elements and organs belonging to a number of different systems that can be affected by a variety of local and systemic pathologic processes. Diagnostic imaging has assumed a central role in the evaluation of this region. In the following monograph, we present the reader with an overview of contemporary maxillofacial imaging, focusing on three areas: recent technical advances that impact on the diagnosis of the maxillofacial region, the appearances of various maxillofacial lesions on different imaging modalities, and an overview of the role of diagnostic imaging in the evaluation of the orthognathic patient. In the first section, we focus on recent technical advances in diagnostic imaging as they relate to the maxillofacial region. Imaging modalities discussed include panoramic radiography and three-dimensional imaging. We also examine the uses of recently developed computed tomography software for the evaluation of the dental implant patient and discuss the roles of both noninteractive and interactive software in this process. The second section focuses on the radiographic appearance of a number of common lesions involving the maxillofacial region. In this section, we use the gamut approach to examine a number of developmental, inflammatory, neoplastic, metabolic, and traumatic lesions or disorders. In the last section, we briefly review the subject of orthognathic surgery and the role of diagnostic imaging in the preoperative and postoperative evaluation of the orthognathic patient. The radiographic appearance of some of the more commonly performed midfacial osteotomies are presented.

Dental Implantation↗

The DNA sequence and comparative analysis of human chromosome 20.

The finished sequence of human chromosome 20 comprises 59,187,298 base pairs (bp) and represents 99.4% of the euchromatic DNA. A single contig of 26 megabases (Mb) spans the entire short arm, and five contigs separated by gaps totalling 320 kb span the long arm of this metacentric chromosome. An additional 234,339 bp of sequence has been determined within the pericentromeric region of the long arm. We annotated 727 genes and 168 pseudogenes in the sequence. About 64% of these genes have a 5' and a 3' untranslated region and a complete open reading frame. Comparative analysis of the sequence of chromosome 20 to whole-genome shotgun-sequence data of two other vertebrates, the mouse Mus musculus and the puffer fish Tetraodon nigroviridis, provides an independent measure of the efficiency of gene annotation, and indicates that this analysis may account for more than 95% of all coding exons and almost all genes.

Animals↗

Identifying pre- and postoperative predictors of cost and length of stay for coronary artery bypass surgery.

Prior studies of resource use for coronary artery bypass graft (CABG) surgery have either focused on a limited number of hospitals or have used charges instead of costs. We used a large statewide database (n = 6791) to study predictors of cost and length of stay (LOS) for CABG surgery. We used linear regression to sequentially model (a) specific procedures performed, (b) preoperative patient characteristics, and (c) postoperative events to determine the relative impact of these 3 factors on resource use. We then used the resulting models to calculate adjusted mean hospital costs and LOS. These 3 factors were all significantly associated with resource use. Postoperative events were the greatest determinant of costs, while preoperative characteristics were the greatest determinant of LOS. Despite risk adjustment for these factors, resource use differed significantly across 12 hospitals (mean cost range, $22,200 to $41,900; mean LOS range, 11 to 18 days), suggesting that some institutions may need to reduce their resource use.

Aged↗