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Biomedical subjects

R E Gold

Publications and source records attributed to R E Gold.

68 records · Page 4Linked to original sources

Angiography in determining the cause and treatment of gastrointestinal bleeding.

Angiography is useful in the diagnosis of active gastrointestinal bleeding if the rate is greater than 0.5 mL/min. For upper gastrointestinal bleeding, endoscopy is the preferred initial investigation and angiography is used for diagnosis only if the site of bleeding is still obscure. Angiography is the preferred method for investigation of massive lower gastrointestinal bleeding if results of sigmoidoscopy are negative. Vasopressin infusion is most useful for control of bleeding from esophageal varices, erosive gastritis and diverticular disease of the colon. Embolization with Gelfoam or clot is possible for massive hemorrhage from a single source in poor-risk patients. This is most successful for gastric or duodenal bleeding since the collateral blood supply prevents infarction. Some of the methods and complications of embolization are discussed and examples are given. Standard surgical principles should still apply in most cases.

Adult↗

Rectal wall bleeding--an overlooked source of massive lower gastrointestinal hemorrhage.

Two cases of acute massive bleeding from the rectum are described. In both cases, the diagnosis was made angiographically. Some points of angiographic technique are discussed. In both cases, there had been previous negative sigmoidoscopy. Care must be taken to include the entire rectum on the films obtained during injection of the inferior mesenteric artery regardless of findings on sigmoidoscopy.

Adult↗

Gelfoam embolization of the left gastric artery for bleeding ulcer: experimental considerations.

A bleeding gastric ulcer was surgically created in 18 dogs, and the left gastric artery was successfully catheterized by percutaneous techniques in 15. Nine of these dogs were treated with vasopressin infusion which did not arrest the hemorrhage. A total of 11 dogs (five of them following unsuccessful vasopressin therapy) underwent embolization with strips of Gelfoam, and hemorrhage stopped in ten. This technique of embolization is concluded to be of value in the management of gastric hemorrhage.

Angiography↗

Creation of a reliable gastric bleed in dogs for angiographic studies.

A method of creating a brisk and reliable bleed from the left gastric artery of the dog has been developed. This has been quantitated and emonstrated by celiac and left gastric arteriography. Such a model lends itself to studies on the pharmacologic or embolic control of bleeding of the stomach.

Angiography↗

Initial experience with a universal-length copolymer ureteral stent.

A universal-length ureteral stent made of a biocompatible copolymer was designed specifically for easy antegrade internal placement. The double-looped distal end of the stent eliminates the need to measure the distance from the ureteropelvic to ureterovesical junction. If additional length is required, a portion of the distal loop is incorporated into the stent shaft. Interventional radiology practices benefit economically, as the universal-length stent is the only size required for the treatment of most ureteral obstructions.

Adolescent↗

Bronchial arteriography and embolotherapy for hemoptysis in patients with cystic fibrosis.

Bronchial arteriography and embolotherapy were performed to control hemoptysis in 11 patients with advanced stages of cystic fibrosis. Two patients suffered massive, 1 moderate, and 8 mild but recurrent hemoptysis. The embolization procedures were performed with Gelfoam, Ivalon, and coils in one to four separate procedures. Altogether, 19 of 20 procedures were successful, with follow-up periods ranging from 9 months to 8 years. No serious complications were encountered except for one femoral artery pseudoaneurysm which required surgical repair. Rapid digital subtraction angiography and "roadmapping" were considered helpful in avoiding the complication of reflux embolization and expediting the procedures. Bronchial embolization is a life-saving procedure for severe hemoptysis in patients with cystic fibrosis and is considered safe enough to include the indications of moderate and mild/recurrent hemoptysis to improve the quality of life in these patients.

Adolescent↗

Distention arthrography in the treatment of adhesive capsulitis of the shoulder.

PURPOSE: Adhesive capsulitis involving the glenohumeral joint (frozen shoulder) is an insidious and painful condition that results in gradual loss of joint motion. Recovery is frequently prolonged despite multiple therapeutic maneuvers. The authors investigate the mechanism of action and the long-term clinical result of distention arthrography for the treatment of patients with frozen shoulder. PATIENTS AND METHODS: Sixteen patients with adhesive capsulitis of the shoulder were treated with therapeutic capsular distention by using intra-articular injection of a 30-mL mixture of lidocaine, corticosteroid, and contrast media immediately following diagnostic arthrography. RESULTS: Capsular disruption was demonstrated in all cases. Thirteen patients (80%) experienced immediate pain relief and increased shoulder mobility. This improvement was maintained over a follow-up interval of 6 months or more. Disruption occurred at the subscapular bursa in eight patients, the subacromial bursa in six, and the distal bicipital tendon sheath in two. These latter two patients had no pain relief. CONCLUSION: Arthrographic distention of the constricted capsule appears to be an excellent therapeutic intervention for achieving rapid symptomatic relief from adhesive capsulitis.

Arthrography↗