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Biomedical subjects

R E Enck

Publications and source records attributed to R E Enck.

At least 37 records · Page 2Linked to original sources
PubMed1983

Community hospital oncology program: an organizational and group process perspective.

The STRCP has successfully completed the CHOP planning phase with medical, nursing, rehabilitation/support guidelines lines as one component of the program. With implementation, data is being collected on guideline use and compliance as well as active PMP updating. An evaluation plan is being implemented. Hopefully with these and other activities, the role of the CHOP as a model for cancer control activities in the community will be clearly defined.

Cancer Care Facilities↗
PubMed1979

Complete remission of widely metastatic endometrial stromal sarcoma following combination chemotherapy.

A 21-year-old female underwent a hysterectomy with the finding of an endometrial stromal sarcoma (7-9 mitoses/10 HPF) confined to the uterus. However, within 30 months of hysterectomy, metastases occurred in the spinal cord, femur and lungs. Treatment consisted of surgery and irradiation for the spinal cord metastases and ten courses of combination chemotherapy, Adriamycin, vincristine, cyclophosphamide (6 courses) and megestrol acetate (continuous since course 7). This therapy resulted in a complete clinical remission which has been maintained for eight months since completion of chemotherapy. It is suggested that this regimen be employed in patients with this rare and lethal tumor.

Adult↗
PubMed1979

Tetracycline-induced aplastic anemia.

A 54-year-old man developed mild renal insufficiency after treatment with gentamicin and cephalothin. He then received tetracycline for eight days, 500 mg orally four times daily, for a total dose of 15 gm. Twelve days after discontinuation of the drug, a severe but reversible aplastic anemia developed. We propose that bone-marrow-toxic concentrations of tetracycline resulted from the preexisting renal insufficiency. Because of the temporal relationship between tetracycline administration and aplastic anemia, and the lack of any other explanation, we conclude that this case illustrates a rare but potentially fatal complication of this drug.

Anemia, Aplastic↗
PubMed1979

Hyperhaptoglobinemia and carcinoma of the gallbladder.

Cancer of the gallbladder is an uncommon malignancy which is seldom diagnosed early and often denotes a poor prognosis. Two reported cases describe the association of hyperhaptoglobinemia (greater than 700 mg./dl.) and advanced carcinoma of the gallbladder. When a patient presents with liver involvement from metastatic adenocarcinoma of suspected gastrointestinal origin and a markedly elevated serum haptoglobin (greater than 700 mg./dl.), it is suggested that a high index of suspicion be held for carcinoma of the gallbladder.

Adenocarcinoma↗
PubMed1976

Adult acute leukemia. The Rochester (NY) Experience.

A ten-year retrospective study of adult acute leukemia was performed in nonieukemia-specialized centers to determine prognostic factors, length and quality of survival, cause of death, and response to different modes of therapy. Of 200 patients, 9.5% achieved complete remission, 14.0% obtained partial remission, and no response was present in 76.5%. Patients who were 50 years old or more (64.5%) had a significantly lower response rate (P less than .005) and survival (P less than .05) than the younger age group. Aggressive chemotherapy significantly improved the response rate, as well as survival (P less than .001). Quality of life was similar for responders and nonresponders, both spending only one fourth of their survival time in the hospital. Infection as the leading cause of death. The overall ten-year response rate of 23.5% represents a realistic rate in nonleukemia-specialized centers in which the treatment of adult acute leukemia is variable.

Acute Disease↗
PubMedDate not supplied

Thanatos.

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Attitude of Health Personnel↗
PubMedDate not supplied

Terminal sedation.

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Procedural Sedation↗