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Biomedical subjects

R E Eilers

Publications and source records attributed to R E Eilers.

At least 19 recordsLinked to original sources

A longitudinal evaluation of the speech perception capabilities of children using multichannel tactile vocoders.

Thirty children (mean age 6:11, range 4:3 to 11:0, SD = 2:3) with profound hearing impairments were followed longitudinally over a 3-year period and evaluated every 6 months with a battery of speech perception tests. The battery spanned several levels of perception, from pattern perception to open-set word recognition. The children were all enrolled in a single full-day educational program that used multichannel tactile aids in addition to hearing aids. Testing was conducted in Auditory alone (A), Tactile plus Auditory (TA), Tactile alone (T), and in one instance, Tactile plus Auditory plus Vision (TAV) conditions because the primary interest of the work was the relationship between auditory and tactile training on perception. Results indicated that children's performance improved with age, with the oldest children achieving open-set speech recognition in the TA condition. Performance in the TA condition generally exceeded that in both A and T conditions. Outcomes were compared to those from two studies in the literature for children of similar age with cochlear implants and tactile aids on the same tests. Results suggest that performance of children who had cochlear implants for an average of 21 months was similar to TA and TAV performance of children in the present study who had tactile experience over a similar period.

Child

Infant vocalizations and the early diagnosis of severe hearing impairment.

To determine whether late onset of canonical babbling could be used as a criterion to determine risk of hearing impairment, we obtained vocalization samples longitudinally from 94 infants with normal hearing and 37 infants with severe to profound hearing impairment. Parents were instructed to report the onset of canonical babbling (the production of well-formed syllables such as "da," "na," "bee," "yaya"). Verification that the infants were producing canonical syllables was collected in laboratory audio recordings. Infants with normal hearing produced canonical vocalizations before 11 months of age (range, 3 to 10 months; mode, 7 months); infants who were deaf failed to produce canonical syllables until 11 months of age or older, often well into the third year of life (range, 11 to 49 months; mode, 24 months). The correlation between age at onset of the canonical stage and age at auditory amplification was 0.68, indicating that early identification and fitting of hearing aids is of significant benefit to infants learning language. The fact that there is no overlap in the distribution of the onset of canonical babbling between infants with normal hearing and infants with hearing impairment means that the failure of otherwise healthy infants to produce canonical syllables before 11 months of age should be considered a serious risk factor for hearing impairment and, when observed, should result in immediate referral for audiologic evaluation.

Age Factors

Speech-like vocalizations in infancy: an evaluation of potential risk factors.

This work reports longitudinal evaluation of the speech-like vocal development of infants born at risk due to prematurity or low socio-economic status (SES) and infants not subject to such risk. Twenty infants were preterm (10 of low SES) and 33 were full term (16 of low SES), and all were studied from 0;4 through 1;6. The study provides the indication that at-risk infants are not generally delayed in the ability to produce well-formed speech-like sounds as indicated in tape-recorded vocal samples. At the same time, premature infants show a tendency to produce well-formed syllables less consistently than full terms after the point at which parents and laboratory personnel note the onset of the canonical babbling stage (the point after which well-formed syllables are well established in the infant vocal repertoires). Further, even though low SES infants produce well-formed speech-like structures on schedule, they show a reliably lower tendency to vocalize in general, as reflected by fewer utterances per minute in recorded samples.

Female

Early vocal development in tactually aided children with severe-profound hearing loss.

The vocalizations of six children with severe-profound hearing loss were audio-recorded in two conditions during individual speech-language intervention sessions: (a) auditory amplification alone, and (b) auditory amplification plus the Tactaid II, a two-channel vibrotactile device (Franklin, 1986). Utterances were categorized according to the infraphonological framework described by Oller (1980, 1986) and Oller and Lynch (1992). Vocalizations were categorized in a developmental framework relative to mature speech. Those utterances containing well-formed consonant-vowel syllables were transcribed with broad phonetic transcription and analyzed at both the syllabic and segmental levels. Statistically significant differences were found between the two conditions for vocal volubility (i.e., quantity of vocalizations produced); subjects vocalized more when using both auditory amplification and the Tactaid II together than with auditory amplification alone. Trends in the early vocal development of these children with severe-profound hearing loss are described at the infraphonologic, segmental, and syllabic levels.

Articulation Disorders

Automated electrophysiologic hearing testing using a threshold-seeking algorithm.

The efficacy of utilizing an automated algorithm to identify auditory brainstem responses (ABR) was studied. A microcomputer-based threshold-seeking algorithm utilizing click-evoked ABR was developed to determine evoked-response thresholds for automated hearing screening. The software consists of an evoked-response recognizer unit, which determines the presence or absence of a response, and a threshold-tracking unit, which controls the click intensity in order to track the threshold. The response recognizer is based upon correlation methods. Threshold tracking is accomplished using a Parameter Estimation by Sequential Testing (PEST) procedure, which is commonly used to study psychophysical properties of the auditory system. Sound level is automatically adjusted, based on the results of the recognizer and the threshold tracker. Test results were generally obtained in less than 15 minutes per ear. The results of the automated procedure correlate very highly with expert judgments of ABR threshold and show good test-retest reliability, suggesting that automated procedures are viable alternatives to traditional testing methods.

Adolescent

Perception of the stop/glide contrast in infancy.

Much of the published research in infant speech perception has emphasized how well infants have done with a number of speech contrasts, and have noted similarities in pattern of discrimination of adults and infants. Often it has been suggested that infants begin life with the ability to perceive any speech contrast, and that the process of acquiring a language involves inhibition of the ability to perceive contrasts not present in the target language. Indeed some studies have shown infants able to discriminate contrasts on which adults fail if the contrasts are not drawn from the native language of the adults. Other studies, however, have suggested that infants may not always be so perceptually capable. The present work focusses on the stop-glide contrast. The results are inconsistent with the prevalent view and with previously reported studies on the perception of the stop-glide contrast by infants. The results indicate that in a vigilance paradigm adapted for both infant and adult testing, infants perform poorly on the contrasts when compared with adults. Furthermore the pattern of relative perception observed in the adults on stimuli with long or short vowels is quite unlike that of the infants. It is concluded that much work remains in order to evaluate the relative performance of infants and adults in speech perception, since it appears that changes in experimental paradigm or particular stimulus parameters may affect outcomes in fundamental ways.

Acoustic Stimulation

Classification of audiograms by sequential testing: reliability and validity of an automated behavioral hearing screening algorithm.

In 1990, CAST (classification of audiograms by sequential testing) was proposed and developed as an automated, innovative approach to screening infant hearing using a modified Bayesian method. The method generated a four-frequency audiogram in a minimal number of test trials using VRA (visual reinforcement audiometry) techniques. Computer simulations were used to explore the properties (efficiency and accuracy) of the paradigm. The current work is designed to further test the utility of the paradigm with human infants and young children. Accordingly, infants and children between 6 months and 2 years of age were screened for hearing loss. The algorithm's efficacy was studied with respect to validity and reliability. Validity was evaluated by comparing CAST results with tympanometric data and outcomes of staircase-based testing. Test-retest reliability was also assessed. Results indicate that CAST is a valid, efficient, reliable, and potentially cost-effective screening method.

Acoustic Impedance Tests

FFT-based digital tactile vocoder system for real-time use.

A microprocessor-based real-time digital vibrotactile vocoder system has been developed to train the deaf and for artificial hearing research. The system is composed of a microcomputer module with a digital signal processor, interface units and an attenuator/driver circuit. Live or digitised (stored or synthetic) speech is presented to the skin spectrally through a belt housing eight or 16 vibrators. Speech is processed in real time using a fast Fourier transform. The system is also capable of presenting any arbitrary spatiotemporal pattern on the skin for artificial hearing experiments. A preliminary experiment with a deaf subject indicates that the system is potentially an effective device for artificial hearing.

Biomedical Engineering

Speech perception in adult subjects with familial dyslexia.

Speech perception was investigated in a carefully selected group of adult subjects with familial dyslexia. Perception of three synthetic speech continua was studied: /a/-/e/, in which steady-state spectral cues distinguished the vowel stimuli; /ba/-/da/, in which rapidly changing spectral cues were varied; and /sta/-/sa/, in which a temporal cue, silence duration, was systematically varied. These three continua, which differed with respect to the nature of the acoustic cues discriminating between pairs, were used to assess subjects' abilities to use steady state, dynamic, and temporal cues. Dyslexic and normal readers participated in one identification and two discrimination tasks for each continuum. Results suggest that dyslexic readers required greater silence duration than normal readers to shift their perception from /sa/ to /sta/. In addition, although the dyslexic subjects were able to label and discriminate the synthetic speech continua, they did not necessarily use the acoustic cues in the same manner as normal readers, and their overall performance was generally less accurate.

Dyslexia

Open-set word identification by an adult with profound hearing impairment: integration of touch, aided hearing, and speechreading.

The ability of an adult with profound hearing impairment to integrate speech information from touch, aided hearing, and speechreading in identification of open-set words was investigated. A list was obtained of 735 words that the subject failed to identify using any single modality: touch, with either the Tacticon 1600, a multichannel electrocutaneous vocoder (TV), or the Tactaid II, a 2-channel vibrotactile aid (TA); aided hearing (H); or speechreading (S). To test integration, observed word identification performance in combined-modality conditions was compared with predicted performance calculated from single-modality scores. Words were randomly assigned to seven conditions: (a) S+H, (b) H+TV, (c) H+TA, (d) S+TV, (e) S+TV+H, and (f) S+TA+H. Results indicated that the subject integrated speech information across modalities, with highest performance in the S+TV+H and S+TA+H conditions. Integration also occurred when both speechreading and touch were used and when both speechreading and aided hearing were used.

Adult

A study of perceptual development for musical tuning.

Musical tuning perception in infancy and adulthood was explored in three experiments. In Experiment 1, Western adults were tested in detection of randomly located mistunings in a melody based on musical interval patterns from native and nonnative musical scales. Subjects performed better in a Western major scale context than in either a Western augmented or a Javanese pelog scale context. Because the major scale is used frequently in Western music and, therefore, is more perceptually familiar than either the augmented scale or the pelog scale are, the adults' pattern of performance is suggestive of musical acculturation. Experiments 2 and 3 were designed to explore the onset of culturally specific perceptual reorganization for music in the age period that has been found to be important in linguistically specific perceptual reorganization for speech. In Experiment 2, 1-year-olds had a pattern of performance similar to that of the adults, but 6-month-olds could not detect mistunings reliably better than chance. In Experiment 3, another group of 6-month-olds was tested, and a larger degree of mistuning was used so that floor effects might be avoided. These 6-month-olds performed better in the major and augmented scale contexts than in the pelog context, without a reliable performance difference between the major and augmented contexts. Comparison of the results obtained with 6-month-olds and 1-year-olds suggests that culturally specific perceptual reorganization for musical tuning begins to affect perception between these ages, but the 6-month-olds' pattern of results considered alone is not as clear. The 6-month-olds' better performance on the major and augmented interval patterns than on the pelog interval pattern is potentially attributable to either the 6-month-olds' lesser perceptual acculturation than that of the 1-year-olds or perhaps to an innate predisposition for processing of music based on a single fundamental interval, in this case the semitone.

Adult

Influences of acculturation and musical sophistication on perception of musical interval patterns.

Influences of acculturation and musical sophistication on music perception were examined. Judgments for mistuning were obtained for Ss differing in musical sophistication who listened to a melody that was based on interval patterns from Western and Javanese musical scales. Less musically sophisticated Ss' judgments were better for Western than Javanese patterns. Musicians' thresholds did not differ across Western and Javanese patterns. Differences in judgments across scales are accountable to acculturation through listening exposure and musical sophistication gained through formal experience.

Acculturation

Optimization of automated hearing test algorithms: simulations using an infant response model.

Computer simulation was used to evaluate several parameters of an automated hearing test algorithm in an attempt to optimize the algorithm for accuracy and efficiency. An infant response model was developed to guide the simulations. Test parameters of interest were starting intensity and stopping rule and their interaction with a measure that is thought to emulate infant reliability, probability of task orientation. Results indicated that stopping rule, within the ranges investigated, had little effect on accuracy but had major impact on efficiency. Starting intensity interacted with the hearing status of pseudosubjects in influencing accuracy. Accuracy was most influenced by probability of task orientation. The simulated test data are compared to data from infants and young children in the accompanying article so that the response model can be evaluated.

Algorithms

Optimization of automated hearing test algorithms: a comparison of data from simulations and young children.

A five-up, five-down automated staircase procedure was used to explore the effects of variable starting and stopping rules as they interact with infant behavior in influencing the accuracy and efficiency of infant auditory threshold testing. Results from 146 infants were compared to results from computer simulations (see accompanying article) in order to evaluate an infant response model used in the simulations. Results indicate that the automated procedure successfully discriminated between infants with normal versus abnormal tympanograms. In addition, the model accurately predicted infant results in terms of the effects of starting and stopping rules. The model was less useful in predicting the relationship between minimum response levels and false positive rates.

Algorithms

The stop/glide boundary shift: modelling perceptual data.

Research in speech perception has suggested that listeners often adjust category boundary locations for differing contexts. The stop/glide (e.g.,/ba/vs./wa/) boundary shift occurring with changes in syllable duration has been interpreted as reflecting 'rate normalization' by some, whereas others have suggested an auditory basis for the shift. Clarification of both the causes and the effects of the stop/glide shift is being sought through experimentation intended to expand our knowledge of variations in the shift across different experimental treatments. The present study extends research on the stop/glide shift by (1) showing that the shift is not an artifact of a particular stimulus pattern that had been present in all the previous studies of the effect, (2) further demonstrating the nonlinear character of the identification shift, (3) providing additional evidence of the role of presentation format (mixed vs. blocked) in the identification shift, and (4) exploring boundary locations in various discrimination paradigms. The complex outcomes of the studies reported here as well as a variety of previous results are interpreted as compatible with expanded versions of the durational contrast hypothesis. Two versions are considered, one in which the shift is seen as due to a mechanism of contrastive perception that applies to events of comparable duration, and one in which the shift is seen as a perceptual error that occurs when the auditory system attempts to track frequency trajectories that change (i.e., pivot) over time.

Adult

Computer methods for on-line hearing testing with auditory brain stem responses.

On-line computer methods were developed and evaluated for automated hearing testing with auditory brain stem responses (ABR). The system contained (1) a response recognition unit which recognized the presence or absence of an ABR response and (2) a threshold tracking unit which adjusted stimulus intensity and determined the ABR threshold. Two methods, one nontemplate (variance ratio) and one template (cross-correlation), were evaluated for response recognition while three threshold tracking methods were explored: clinical, Békésy, and PEST (parameter estimation by sequential testing). Both response recognition and threshold tracking units were evaluated by computer simulations for on-line operation using a standard set of experimentally recorded ABRs. The results indicated that while all the response recognition methods were reasonably accurate, their on-line use resulted in significant differences in test efficiency due to differences in tracking methods.

Acoustics

Classification of audiograms by sequential testing using a dynamic Bayesian procedure.

A new method for estimating audiograms using behavioral responses is presented. The method is based upon a modification of the Bayesian probability formula in which an outcome is predicted from a static set of events. In the new method, classification of audiograms by sequential testing (CAST), the probabilities of occurrence of audiogram patterns are dynamically updated according to the outcome of each test trial. Computer simulation using an infant response model suggests that the procedure is efficient, sensitive, and specific.

Algorithms