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Biomedical subjects

R E Davis

Publications and source records attributed to R E Davis.

At least 325 records · Page 18Linked to original sources

Pregnancy and untreated Addisonian pernicious anemia.

The case histories are given of two patients, aged 38 and 35 years, who conceived while suffering from Addisonian pernicious anaemia. The relationship of these findings to the routine use of folic acid during pregnancy is discussed.

Adult↗

Remission of aster yellows disease by antibiotics.

Suppression of symptoms of aster yellows by antibiotics supports the tentative hypothesis that the etiologic agent is a mycoplasma-or bedsonia-like organism rather than a virus. Development of symptoms was supressed by chlortetracycline, tetracycline, or chloramphenicol, but not by penicillin. When plants were treated with chlortetracycline at 1000 parts per million before symptoms appeared, symptoms developed only after cessation of the treatment. Assay of the agent of aster yellows, extracted from plants, indicated inhibition of growth of the pathogen by treatment with chlortetracycline. Plants severely affected before treatment began developed new symptomless axillary growth, including flowers; previously yellowed leaves often became green. Acquisition of the agent of aster yellows by leafhoppers was drastically reduced when infected plants were treated with chlortetracycline continuously for 1 week before exposure to the vectors. Our data, and preliminary evidence from purification studies, are consistent with a possible mycoplasma-or bedsonia-like etiology of the aster yellows disease.

Chlamydia↗

Actinomycin D blocks formation of memory of shock-avoidance in goldfish.

When 2 micrograms of antinomycin D was injected intracranially into goldfish immediately after a training session, the formation of long-term memory of a shock-avoidance was blocked. The results are discussed in relation to similar findings with acetoxycycloheximide and puromycin in the goldfish and with apparently conflicting results in the mouse.

Animals↗