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Biomedical subjects

R Dore

Publications and source records attributed to R Dore.

At least 55 records · Page 3Linked to original sources
PubMed1988

[Computerized tomography in surgically treated lumbar disk hernia. Multicenter study].

Results are reported of a multicenter analytic-statistical CT study on 128 postoperative lumbar herniated disk (HD) cases (50 at L4-L5, 64 at L5-S1, 2 at L3-L4, 12 multiple). CT was performed from 10 days to 204 months (47.7 months of mean) after surgery, in 51 patients without and in 77 with intravenous contrast medium (42 in bolus, 35 in perfusion). In 59 cases (38%) a recurrent hernia was found, and in 8% a new hernia. In 81% of patients epidural fibrous scars were demonstrated, in a rough 50% of cases associated with recurrent/new hernia: posterior fibrosis was found in 81% of cases, while unilaterally, bilaterally, or anteriorly extended fibroses were present in 20%, in 4.7%, and in 29% of cases respectively. In 72% of the patients injected with contrast medium, various kinds of fibrosis contrast enhancement were detected. In 8% neither fibrosis nor recurrent herniation was found. In 22% of cases lateral and/or central bony canal stenosis was present, in 26% vacuum disk, in 9% intracanalar calcifications, in 39% and in 19.5% dural sac stretching and compression respectively. In 5 cases a pseudomeningocele was found, and in 3 only a postoperative diskitis. Fibrosis is an almost inevitable postoperative consequence (4 out of 5 cases); it can be demonstrated by CT with high sensitivity and good specificity. A series of diagnostic criteria, such as the post-contrast media reaction, allow fibrosis to be discriminated from recurrent hernia. However, the possible association must be kept in mind of both diseases and/or of included roots in the scar. Myelography is hardly ever able to supply further resolutive diagnostic elements, while Myelo-CT is sometimes more useful. The importance of bone changes is questionable, with the exception of evident cases of canal stenosis, also because in most cases the radiologist cannot count on a preoperative CT study. Furthermore, the correlation between CT and clinical findings (possible asymptomatic fibrosis) is often difficult, which gives way to contrasting therapeutic attitudes.

Adult↗
PubMed1987

[Thrombosis of the false lumen in acute aortic dissection. CT diagnosis].

Three cases are reported of acute aortic dissection with complete thrombosis of the false channel, which is a very uncommon event in De Bakey's I and II type aortic dissections. The 3 patients entered hospital because of severe thoracic pain without any ECG sign of myocardial infarction. Emergency CT showed evidence of pericardial effusion suggesting hemopericardium, enlargement of the ascending aorta and a peripheral semilunar filling defect which caused a slight deformation of the true channel. On precontrast scans, only one case showed inward displacement of peripheral intimal calcifications and high-density aortic wall. No typical signs of aortic dissection were reported, except in the first patient--where a double contrast filled lumen, separated by an intimal flap was seen. CT findings are individually discussed. It is emphasized that in all patients more than one CT sign was present at a time. The correct evaluation of these signs together with the clinical data could lead to the right diagnosis of aortic dissection in spite of the lack of a filled false channel.

Acute Disease↗
PubMed1987

[Quantitative computerized tomography of the vertebral spongiosa. Proposal of a method applicable to the study of postmenopausal osteoporosis].

A Quantitative Computed Tomography (QCT) method, simplifying the well-known technique proposed by Genant (1982) and applied to a standard third generation whole body CT scanner is described. This technique was applied in the measurement of the trabecular bone which has high sensitivity for metabolic changes. The BMC (Bone Mineral Content) measured in different groups of subjects (healthy postmenopausal patients versus women with postmenopausal osteoporosis) showed a highly significant difference (p less than 0.001). The precision of repositioning (coefficient of variation 1.8% to 2.3%, obtained in healthy male patients) and the good, linear relationship computed from the phantom values, minimize measurement errors. Since this method is quickly applied and involves low-dose radiation-exposure, it could be introduced in the clinical study of metabolic bone diseases.

Female↗
PubMed1986

[Updating the diagnosis of neonatal cerebral pathology. Comparison of ultrasonic diagnosis and CT x-ray in hemorrhage-ischemia-anoxia].

The authors compare the accuracy of Ultrasound and Computed Tomography in the diagnosis of hypoxic-ischemic brain damage and intracranial haemorrhage in 25 newborns with respiratory distress syndrome. Both examinations are performed at a maximum interval of 48 hours, within the first 8 days of life, and lately, after the third week. The results allow the introduction of a diagnostic protocol.

Age Factors↗
PubMed1986

[Serous-papillary carcinoma of the endometrium. Usefulness and limitations of computerized tomography].

The staging of endometrial carcinoma and the evaluation of tumor recurrences take advantage from Computerized Tomography (CT). The CT appearances are described of six new cases and two recurrences of uterine papillary serous carcinoma (UPSC), which is a particularly aggressive and rare form of endometrial carcinoma. CT has been scarcely useful in first clinical stages, while in advanced stage and when the tumor appears as a pelvic mass CT has allowed to recognize the uterine origin, to define the involvement of surrounding tissue and to depict the extrauterine spread patterns. CT has been extremely useful in the evaluation and in the search for tumor recurrences.

Carcinoma, Papillary↗
PubMed1985

[Rapid identification of Enterobacteriaceae: evaluation of 3 commercial systems].

We have compared three rapid systems for the identification of Enterobacteriaceae: MS-2, Rapid 20E, Micro-ID. These methods allows to identifications of bacteria within 4-5 hours. We have chosen API 20E as reference system; because it is normally used in the clinical microbiology laboratories. We have noted good agreement of concordance for MS-2, Micro-ID and Rapid 20E towards API 20E, respectively 95, 90, 84%. We have, moreover, analysed significative difference about three systems biochemical tests in comparison with the same of API 20E.

Enterobacteriaceae↗
PubMed1984

[Computerized tomography in the study of malignant tumors of the larynx].

A systematic investigation was carried out on 93 patients suffering from laryngeal tumours who underwent computed tomography and xeroradiography. A comparison is made between CT, xerographic, clinical and endoscopic findings. The value is stressed of functional informations obtained from CT performed during quiet breathing and phonation. The outstanding value of CT is the accuracy in definition of tumor extension and involvement of the laryngeal and paralaryngeal tissues. CT can be useful in diagnosis of regional lymph nodes metastases. The correct evaluation of the tumour is greatly helpful in surgical treatment and radiotherapy planning.

Epiglottis↗
PubMed1984

[X-ray computed tomography in non-neoplastic pathology of the larynx].

The authors describe the CT findings in 57 patients suffering from various non-neoplastic disease of the larynx: chronic laryngitis, pseudotumor, paralysis, post-traumatic lesions, laryngocele, cyst. CT is usefull in evaluating site and extension of the disease, as well as its relations with the surrounding tissues. The densitometric evaluation and the functional tests are important in differential diagnosis with malignant neoplasms.

Adolescent↗
PubMed1982

[Computerized tomography in studies of the larynx. Normal anatomy].

The CT picture of the normal larynx was studied in 15 volunteers free from laryngeal disorders and in 142 patients examined at the level of the neck for a variety of pathological conditions. The investigation was carried out during normal breathing and during phonation. The diagnostic importance of these two functional attitudes is stressed. Tomographic anatomy was described according to axial planes: suprahyoid, hyoid, subhyoid, supraglottic, glottic and subglottic. In addition to the laryngeal structure, the cartilaginous skeleton and the anatomical formations surrounding the larynx were also investigated. CT was found to be a very useful and accurate tool for studying the delicate structures which form the larynx.

Adult↗
PubMed1979

[Dynamic characteristics of hockey sticks and efficacy of shooting in ice hockey].

Previous studies have established that efficiency in shooting is influenced partly by the dynamic characteristics of the stick being used and partly by the morphology of the player. The purpose of the present study was therefore to verify the hypothesis stating that flexible sticks were superior to rigid ones in respect to the proficiency of shooting of pee-wee hockey players. This study has confirmed the superiority of the flexible stick over the rigid one in terms of speed and accuracy of shooting among pee-wee hockey players. Moreover morphological parameters and muscular strength were found to play a determining role in efficiency of shooting. In fact, it was suggested that the smaller and weaker the player the more advantageous is the use of a flexible stick. Through the use of strain gages fixed to the experimental hockey sticks, it was possible to determine that the speed of shooting is directly related to the acceleration imparted to the stick during the forward phase of the movement. It was also possible to demonstrate that for a given speed of the puck the more flexible stick required a smaller force than the rigid one.

Anthropometry↗
PubMedDate not supplied

Residual mediastinal widening following therapy in Hodgkin's disease.

The chest radiograms (CXR) of 102 patients with Hodgkin's disease presenting with mediastinal involvement at diagnosis were reviewed to assess the incidence and relevance of residual mediastinal abnormalities after therapy. All patients had completed planned treatment and had no evidence of persisting extramediastinum disease at restaging. Thirty-nine cases (38 per cent) showed residual mediastinal widening at the end of therapy (minimal changes in nine and measurable changes in 30 cases). Neither presenting features nor treatment modality correlated with residual mediastinal mass on chest X-ray. The isolated intrathoracic relapse rate was 11 per cent for patients with normal mediastinum following therapy, as compared with 20.5 per cent for those with residual widening; this difference did not reach statistical significance (p = 0.3). The persistence of mediastinal abnormalities was associated with a trend towards a higher risk of intrathoracic relapse for patients with initial bulky disease (p less than 0.05) and for those with B symptoms (p = 0.07). Using thoracic CT scan for restaging (56 patients), the residual mediastinum rate rose to 70 per cent; the predictability of local relapse with this procedure was not greater than with conventional X-ray study.

Adult↗
PubMedDate not supplied

Efficacy and safety of etodolac and naproxen in patients with osteoarthritis of the knee: a double-blind, placebo-controlled study.

A multicenter, parallel-group, double-blind, randomized, outpatient study compared the efficacy and safety of etodolac versus naproxen in patients with osteoarthritis of the knee. After a washout period free of nonsteroidal anti-inflammatory drugs, 254 patients self-administered etodolac 400 mg (n = 86), naproxen 500 mg (n = 82), or placebo (n = 86) twice daily for 4 weeks. Compliance exceeded 90% in all three groups. Primary efficacy variables improved progressively from baseline in all three groups. The extent of improvement was greater in the etodolac and naproxen groups than in the placebo group (P < or = 0.003), except with respect to target joint tenderness (P = 0.028, etodolac vs placebo; P = 0.013, naproxen vs placebo). There were no statistical differences between active treatment groups (P > 0.1). At end point, twice as many patients responded in the etodolac (59%) and naproxen groups (51%) than in the placebo group (26%; P < or = 0.01). There were no significant between-group differences in the numbers of patients who had an adverse experience, a serious adverse experience, or an adverse experience leading to study discontinuation; there were also no significant between-group differences in the distribution of adverse experiences. There were no unexpected clinical or laboratory experiences. Etodolac 400 mg twice daily was as effective and safe as naproxen 500 mg twice daily and both were superior to placebo in the management of osteoarthritis of the knee.

Anti-Inflammatory Agents, Non-Steroidal↗
PubMedDate not supplied

Primitive mucinous cystadenocarcinoma of the retroperitoneum. Case report and diagnostic considerations.

The combination of ultrasonography (US) and computed tomography (CT) proved useful in recognizing and defining the characteristics of a primitive mucinous cystadenocarcinoma of the retroperitoneum, a rare anatomopathological finding which consistently presents certain macroscopic features that help in the formulation of a diagnosis with imaging techniques.

Cystadenocarcinoma, Mucinous↗
PubMedDate not supplied

Unusual osseous changes in lumbar herniated disks: CT features.

Osseous changes in cases of lumbar herniated disks including erosion of the posterior vertebral body cortex near the herniated disk, spinal canal and intervertebral foramen enlargement, and focal sclerosis of the adjacent body are described. The changes were observed in four patients with large and old herniated disks.

Adult↗
PubMedDate not supplied

CT evaluation of myometrium invasion in endometrial carcinoma.

Myometrium invasion (M) is one of the principal prognostic factors in the early clinical stages of endometrial carcinoma and can be evaluated presurgically only by CT, although with conflicting results. We compared CT of 65 patients with early clinical stage endometrial carcinomas with the corresponding anatomopathological findings. Myometrial infiltration of the same degree may present different CT images. Therefore, we identified five fundamental CT patterns, each of which corresponded to one of the three degrees of myometrium infiltration (M1, M2, M3). Furthermore, we defined the infiltration index as the ratio of minimum free myometrium to maximum free myometrium. Overall diagnostic accuracy was 76%; however, for clinical purposes CT provided adequate guidelines for therapeutic decisions in 93% of the cases. These criteria proved to be less reliable in elderly women with atrophic myometria, especially when the neoplasia was polypoid in shape.

Adenocarcinoma↗