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Biomedical subjects

R Donzelli

Publications and source records attributed to R Donzelli.

At least 37 records · Page 2Linked to original sources
PubMed1987

[Experimental giant arterial aneurysm. Resection and reconstruction of the arterial wall].

The authors describe 3 experimental techniques for the treatment of giant arterial aneurysm, based on removal of the aneurysmal pouch and reconstruction of the arterial wall. The aneurysm is realized with a venous graft implanted with end-to-side anastomosis on the common carotid artery on the rabbit. In the first experimental model it is resected along its basis; the arterial wall is reconstructed by means of a patch of dural substitute (dacron coated with silicone rubber) fixed with biological glue (human fibrine). In the second model, the experimental aneurysm is hooded with a venous graft sutured to the adventitia of the artery with four angular stitches and biological glue. The artery is then clamped, the aneurysm is resected along its basis. The median incision in the venous graft is sutured, restoring the continuity of the arterial wall. In the third model, a small artery is implanted at the bottom of the aneurysmal sac, realizing a condition similar to a collateral vessel arising from an aneurysm. In this case, too, the aneurysm is hooded by a venous graft fixed only to the adventitia of the arterial wall with the above mentioned technique. The main and the collateral vessels are clamped, and this latter is severed; the aneurysm is resected along its basis; the median incision in the venous graft is sutured, restoring the continuity of the arterial wall; the collateral vessel is re-implanted along the suture line. These techniques aim to realize the reconstruction of the arterial wall without stenosis and shortening the clamping time.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1986

Posterior fossa hemangioblastomas.

The authors report 40 personal cases of infratentorial hemangioblastomas and review 36 series from the literature for a total number of 1023 patients. The clinical, pathological, and surgical features of these tumors are discussed, with particular consideration of localizations outside the nervous system, multicentric tumors, recurrences, and long-term results. Although hemangioblastomas are benign tumors, their high growth potential makes their long-term development unpredictable in some cases.

Adolescent↗
PubMed1986

Arachnoid cyst of the quadrigeminal cistern.

Arachnoid cysts of the quadrigeminal region are rare. We report two new cases. The first is a 29-year-old woman, who had a recurrence five years after sub-total removal of the cyst wall. Initially it was communicating and was treated by a ventriculo-atrial shunt; later it became noncommunicating and direct drainage of the cyst cavity was required. The second was a 25-year-old female, successfully treated by wide removal of the cyst wall thus creating a large communication with the subarachnoid space. Diagnosis of these lesions, as regards either morphological or functional features, nowadays rests largely on CT. Choices about treatment are extremely difficult. The most radical one, namely, complete removal of the capsule, is not without risks and disadvantages. More prudent methods, such as partial removal of the capsule and/or drainage of the cyst and the ventricles, seem on the whole to be preferable, but careful pre- and post-operative evaluation of CSF dynamics are essential for a satisfactory and long-lasting outcome.

Adult↗
PubMed1986

[Experiences in experimental microneurosurgery].

The authors present their experiences in experimental micro-neuro-surgery referring to the last 2 years. In the field of vascular microsurgery, they explored: the possibility of performing end-to-side anastomoses reducing to few minutes the blood flow interruption in the receiving vessel; experimental reconstructive techniques of the arterial wall in case of giant aneurysm; micro-anastomoses between vessels with calibre smaller than 1 mm. The possibility of carrying out nervous anastomoses between intercostal and lumbar nerves to re-innervate these latter has been also examined on the basis of experimental trials.

Animals↗
PubMed1985

Subarachnoid hemorrhage due to a spinal neurinoma.

A rare observation of spinal neurinoma associated with subarachnoid hemorrhage is reported and the other 12 cases in the literature are reviewed. The extramedullary location of the tumor and the feeble arachnoidal attachments to the spinal cord favor subarachnoidal bleeding in these cases. When the meningeal signs are evident and signs of spinal cord impairment are still unclear, an intracranial origin of the bleeding must be excluded. In doubtful cases, selective spinal angiography is useful in the differential diagnosis between a bleeding spinal tumor and an arteriovenous malformation of the spinal cord.

Aged↗
PubMed1985

Giant intradiploic epidermoid cysts of the skull. Report of two cases.

The authors describe two cases of giant intradiploic epidermoid cysts of the cranial vault in which there was massive intracranial extension causing signs of neurological involvement. The very slow growth and the benign histological nature of these tumors explain their long preoperative evolution and the mild neurological signs in some cases. Roentgenographic and computerized tomography findings permit a correct diagnosis. Complete removal of these cysts and their capsules can be easily accomplished, despite their large size. Total removal of these cysts is associated with a very good long-term prognosis.

Epidermal Cyst↗
PubMed1985

[End-to-side anastomosis made with a short circulatory interruption in the receiving vessel. Experimental model in the rat].

End to side microsurgical anastomoses between vessels of small calibre require interruption of blood flow of about 25-40 min. In terminal vascular beds this time may be incompatible with the cellular survival. The authors refer their experience in rats with a partly original experimental technique requiring less time of clamping the receiving vessel (about 3-4 min), as the main part of the anastomosis is performed between the wall of the donor vessel and the adventitia of the receiving vessel, without interruption of blood flow in this latter. Histological examinations, performed 21 days later, reveal a patency rate of 60%.

Angiography↗
PubMed1984

Lumbar disk. Surgical tricks for safeguarding the "root's ecology".

Restoration of a physiologic periradicular environment is a fundamental step toward improving the results of surgical procedures on the herniated lumbar disk. Combined with the preservation of periradicular fat (or free transplant of subcutaneous fat), reconstruction of the yellow ligament, recreating the interlaminar plane, may act as a barrier against postoperative adhesions. An operative technique is described that is aimed toward preserving the yellow ligament with the purpose of reconstructing it at the end of the surgical procedure on the root.

Humans↗
PubMed1983

Double-contrast enema in antibiotic-related pseudomembranous colitis.

Pseudomembranous colitis (PMC) is a potentially fatal disease often associated with antibiotic therapy. The condition is now known to be due to an enterotoxin produced by Clostridium difficile. Diagnosis is based on the endoscopic finding of the typical pseudomembranes, stool culture, and assay of the stools for the specific toxin. Radiography with double-contrast medium (DCE), which can be performed in patients not critically ill, often yields pathognomonic findings and permits early diagnosis.

Aged↗
PubMed1983

Spinal metastases with neurological manifestations. Review of 600 cases.

The authors have studied 600 cases of spinal metastasis causing a neurological syndrome. The most significant statistical data are reviewed. The cases are examined according to clinical characteristics, type of primary tumor, site of lesion, and survival. Each of these factors influenced the choice and results of treatment. As a general rule, combined treatment (surgery and radiotherapy) was used. Preliminary surgery was performed as an emergency, designed to halt progression of the neurological syndrome and to prevent its more serious manifestations. The technique and usefulness of surgery are discussed for different situations and the short-term results of treatment are related to the various factors involved.

Adolescent↗
PubMed1981

Benign intrasellar cysts.

Four cases of benign intrasellar cysts are reported. Three of these were treated surgically. Their origin and typical clinical features are discussed, in particular the altered pituitary function and visual disturbances. Computerized tomography has many advantages over traditional neuroradiological tools in reaching a diagnosis. The indication for active treatment and the surgical techniques and the methods used in the prevention of complications are outlined.

Adult↗
PubMed1981

Surgical features of cranial metastases.

This study comprises 14 patients with metastatic involvement of the cranium treated between 1957 and 1979. Anatomical and radiological aspects and the clinical manifestations of these metastatic lesions are analyzed. These lesions are not a definite clinical entity, and they have specific therapeutic problems. Treatment consisted of surgical excision and radiotherapy. The surgical results are presented and discussed.

Adolescent↗
PubMed1979

Primary sellar chondromas.

Two cases of chondromas arising primarily from the sella turcica are reported. The eight cases reported in the literature are reviewed. The basic clinical and radiological findings of these tumors and the difficulties of diagnosis and treatment are discussed.

Adolescent↗