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Biomedical subjects

R Dietz

Publications and source records attributed to R Dietz.

At least 343 records · Page 19Linked to original sources
PubMed1976

Does the renin-angiotensin system contribute to the vascular lesions in renal hypertensive rats?

1. Renal hypertensive rats with a normal or suppressed activity of the renin-angiotensin system develop vascular lesions which are similar to those observed in spontaneously hypertensive rats on high sodium diet. 2. Exposure of a vascular bed to high blood pressure results in a rapid damage of the vascular wall, irrespective of the state of the renin-angiotensin system.

Angiotensin II↗
PubMed1976

Changes in vascular smooth muscle sensitivity to vasoconstrictor agents induced by corticosteroids, adrenalectomy and differing salt intake in rats.

1. Isolated hind limbs of rats were perfused and vascular smooth muscle sensitivity to noradrenaline, methoxamine and potassium chloride was measured and dose-response curves were obtained. 2. The sensitivity of vascular smooth muscle to noradrenaline is attenuated by adrenalectomy and low sodium diet; it is enhanced by corticosterone. High sodium diet or administration of deoxycorticosterone did not alter the dose-response curve significantly. 3. The increased sensitivity of vascular smooth muscle after corticosterone treatment is not related to changes in the contractile protein or alterations in the neuronal uptake and extraneuronal metabolism of noradrenaline. 4. These results suggest that the increased sensitivity in corticosterone-treated rats may be due to the number of receptors, receptor affinity to noradrenaline, or changes in the functional link between receptor and contractile apparatus.

Adrenal Cortex Hormones↗
PubMed1976

[Radiotherapy of pinealoma].

The possible methods of radiation therapy of the pinealoma are treated with regard to two own cases. The methods used by other therapeutists are also taken into consideration. The dose distribution in the target volume and the surrounding volume is discussed for different irradiation methods. The troubles felt by the two persons (a girl of 15 years and a boy of 15 years) were declining continually during the radiation therapy.

Adolescent↗
PubMed1975

The renin-angiotensin system in acute renal failure of rats.

1. Acute renal failure was produced in rats by intramuscular injection of glycerol. Subsequently, changes in the concentrations of renin and of angiotensin II in plasma and the renin content of the kidneys were followed. 2. at 4 and 8 h after glycerol administration, plasma renin and angiotensin II had increased two to three-fold; they remained elevated for 48 h and then returned towards normal. At 7 days, the values were still slightly raised. 3. At 4 and 8 h after glycerol injection, kidney renin had decreased but it had increased after 24 and 48 h. 4. Passive immunization with angiotensin II antibodies, given at the time of glycerol injection and 2 and 4 h afterwards, prevented the development of acute renal failure. When angiotensin II antiserum was administered later (8, 10 and 12 h after glycerol) it had no effect. 5. Stimulation of the renin-angiotensin system may be involved in the pathogenesis of the early phase of acute renal failure.

Acute Kidney Injury↗
PubMed1975

Aldosterone and corticosterone production in renal hypertensive rats.

The development of hypertension, which had been elicited by clamping one renal artery in the presence of an untouched contralateral kidney, has been pursued in rats for up to six weeks after operation, and aldosterone and corticosterone production was studied at various intervals.

Aldosterone↗
PubMed1975

[Differential diagnosis of struma maligue].

With reference to a case in which the scintigram showed an autonomous adenoma with a cold area that histologically, however, turned out to be a carcinoma of the thyroid gland, the diagnostical problems of thyroid cancer and the various possibilities in the differential diagnosis are demonstrated.

Adenoma↗