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Biomedical subjects

R Decker

Publications and source records attributed to R Decker.

At least 163 records · Page 9Linked to original sources
PubMed1977

Incidence of HBsAg, anti-HBs and subtypes ad and ay in a general hospital: correlation with clinical data and its significance as a public health problem.

During a period of four months, 9,418 individuals, comprising new hospital admissions, new employees and blood donors, were tested for HbsAg and 1,212 for anti-HBs. A high incidence of positivity for both was found in the different groups under investigation. Subtyping was carried out on acutely ill patients and carriers. Sbtype ay was common in acutely ill patients and among addicts and subtype ad in nonhepatitis patients and healthy carriers. The significance of these findings and possible measures for prevention of spread of the infection are discussed.

Antibodies↗
PubMed1976

Post-traumatic hepatic dysfunction as a major etiology in post-traumatic jaundice.

Thirty-eight patients who had sustained acute trauma, profound hemorrhagic shock, and massive transfusion were studied prospectively to determine the predominant etiologic factors in the development of post-traumatic jaundice. An analysis of clinical and biochemical factors occurring in association with each bilirubin peak in the postoperative course found the jaundice related to transfusion and surgery in 11 instances, to sepsis and septicemia in 15 instances, and to hepatic dysfunction in 23 instances. Results indicated that admission estimates of SGOT and LDH levels, the height of the bilirubin peak and the postoperative day on which it occurs, and the white cell count and GGT at the time of the peak may be of use in the differential diagnosis. Four case reports were used to emphasize the fluctuating pattern of jaundice and the different etiologic factors that may predominate. Light and electron microscopy from three patients illustrated the structural alterations that accompany the biochemical impairment of liver function and enable a more precise appreciation of this syndrome. Hepatic dysfunction appears to be implicated in a high proportion of patients who develop post-traumatic jaundice, which frequently occurs as part of a spectrum of multiple organ failure.

Adolescent↗