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Biomedical subjects

R David

Publications and source records attributed to R David.

At least 253 records · Page 14Linked to original sources
PubMed1976

Pigment deposition in the reticuloendothelial system after fat emulsion infusion.

In 2 infants who had received Intralipid fat emulsion as part of a total parenteral hyperalimentation regimen, a pigmented material was deposited in the macrophages of their reticuloendothelial systems. The histochemical characteristics of this pigment were similar to those seen after experimental infusion of fat emulsions. The possible implications of this finding and its effect on host resistance are briefly considered.

Humans↗
PubMed1976

Plasma cortisol suppression response in the South African black population with glaucoma.

Plasma cortisol suppression was measured in 25 Black glaucomatous patients and in 19 Black patients of similar age and sex, but without glaucoma, who acted as controls. Initial serum cortisol levels were found to be slightly higher in the glaucomatous group. The response to systemically-administered cortisone was statistically more marked in the glaucomatous patients compared with the control group.

Adult↗
PubMed1976

Amyloid-like material in odontogenic tumors.

Various types of odontogenic tumors (epithelial, mesodermal, and mixed tumors) were studied for the presence of amyloid material. Highman's Congo red and Wolman's standard toluidine blue methods were used for diagnosing amyloid. Of all types of odontogenic tumors studied, only the calcifying epithelial odontogenic tumors contained material that might be interpreted as amyloid-like.

Adult↗
PubMed1976

Anterior uveitis and leptospirosis.

Seven patients with anterior uveitis due to leptospirosis are presented. The diagnosis was based upon serologic tests and exclusion of other etiologic possibilities. Six patients came from a well-known endemic area of leptospirosis during the time of epidemics and one case came from an area which was not known to be endemic at the time. In 5 patients the uveitis was bilateral. The disease was mild in all but 2 patents who needed systemic administration of steroids. The posterior part of the eye was not involved in any of the cases.

Adolescent↗
PubMed1975

Early diagnosis of congenital adrenal hyperplasia by measurement of 17-hydroxyprogesterone.

Plasma 17-hydroxyprogesterone was measured by a simple radioimmunoassay technique in six infants, aged 3 days to 3 months, with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Hormonal levels in this group were compared to those of twenty normal newborns and to those found in sixty samples of umbilical vein blood from normal deliveries. Plasma 17-hydroxyprogesterone concentrations were markedly elevated in all congenital adrenal hyperplasia infants (range 544.7-1837 nmol/l, normal 3.03-19.06) at a time when urinary studies in some of these were either not diagnostic or inconclusive. In one infant whose cord blood was analysed, the level was also greatly raised. The data suggest that early definitive diagnosis of congenital adrenal hyperplasia can be established by measurement of plasma 17-hydroxyprogesterone.

Adrenal Glands↗
PubMed1975

Sexual precocity associated with a hypothalamic tumour. Effects of sex hormone therapy.

A case of sexual precocity of unusually early onset and associated with a hypothalamic tumour is described. The effects of ethinyl oestradiol and medroxyprogesterone acetate treatment have been monitored by plasma testosterone, FSH, and LH estimations. The results suggested a partial suppression of the tumour's influence, the mechanism of which is discussed.

17-Ketosteroids↗
PubMed1975

Systemic amyloidosis in Behçet's disease.

Clinical features in two patients with Behcet's disease were dominated by "minor" manifestations of the disease--arthritis and central nervous system involvement in one, chronic stasis ulcers complicating thrombosis of the inferior vena cava in the other. In a third patient, the dominant clinical features were coincidental obstructive airway disease and cor pulmonale. Two patients developed a nephrotic syndrome; the third had intermittent trace proteinuria. Amyloidosis was proved by histologic examination in all three. The two patients examined post-mortem had no focus of chronic suppuration. There is a possibility that systemic amyloidosis is an intrinsic feature of Behcet's disease.

Adolescent↗