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Biomedical subjects

R D Weber

Publications and source records attributed to R D Weber.

At least 91 records · Page 5Linked to original sources

Uses of mediastinoscopy.

The value of mediastinoscopy based on experience gained in over 100 patients is reviewed. Reasons for the routine use of mediastinoscopy in the preoperative evaluation of carcinoma of the lung are presented. This modality is useful in the diagnosis of other nonvascular superior mediastinal masses, especially sarcoidosis and the lymphomas.

Adenocarcinoma↗

Cardiac conduction abnormalities and atrial arrhythmias associated with salicylate toxicity.

Cardiac side effects from aspirin are uncommon; however, severe acid-base imbalance, pulmonary edema, ventricular ectopic activity and cardiopulmonary arrest have been reported in patients with toxic serum salicylate concentrations. We saw a patient with salicylate toxicity who developed a variety of sinus and atrioventricular nodal conduction disturbances and atrial arrhythmias with a relatively low toxic serum salicylate concentration. The cardiac rhythm returned to normal as the serum salicylate concentration decreased, and results of subsequent electrophysiologic testing and Holter monitoring were normal. A low serum albumin level may have resulted in altered salicylate binding in this patient, thereby increasing the availability of unbound (active) drug for toxic effects.

Aged↗